Table 1

Fixed proportions, equieffective and theoretically additive, used for the combination of both drugs

Fixed proportions

n

Equieffective dose (μg)

Theoretically additive (μg)

PPF

(±)-CPP

PPF + (±)-CPP

1

6

1.42

3.97

5.39

1/3

6

0.47

1.32

1.79

1/10

6

0.14

0.4

0.54

1/30

6

0.05

0.13

0.18

1/100

6

0.01

0.04

0.05

N, number of rats.

Morales et al. Arthritis Research & Therapy 2012 14:R196   doi:10.1186/ar4030