Table 1

Baseline gout risk factors by baseline anemia status in the ARIC study.

No anemia

Anemia


Baseline gout risk factors

N = 9,707

N = 1,084


Male sex, n (%)

4,315 (44)

364 (34)**

Mean age, years (SD)

53.9 (56)

53.1 (6)**

African American race, n (%)

1,738 (18)

549 (51)**

Hypertension, n (%)

2,878 (30)

344 (32)

Diuretic use, n (%)

1,478 (15)

160 (15)

Diabetes, n (%)

834 (9)

94 (9)

Coronary heart disease, n (%)

304 (3)

37 (3)

Congestive heart failure, n (%)

209 (2)

30 (3)

Mean BMI, kg/m2, (SD)

27.4 (5)

27.5 (6)

Mean ethanol intake, grams/week, (SD)

41.9 (90)

25.9 (62)**

eGFR, n (%)

<60 ml/min/1.73m2

186 (2)

28 (3)

60 to 90 ml/min/1.73m2

4,140 (43)

337 (31)

≥90 ml/min/1.73m2

5,381 (55)

719 (66)**

Education level, n (%)

<12 years

1,755 (18)

274 (25)

12 to 16 years

4,162 (43)

418 (39)

17 to 21 years

3,781 (39)

388 (36)**

Mean serum uric acid, mg/dL (SD)

5.9 (2)

5.7 (2)**

Incident gout, n (%)

224 (2.3)

47 (4.3)**


* P-value <0.05 ; ** P-value <0.001 comparing anemia to no anemia. Anemia was defined as hemoglobin <13.5 g/dL for men and <12 g/dL for women.

McAdams-DeMarco et al. Arthritis Research & Therapy 2012 14:R193   doi:10.1186/ar4026

Open Data