Table 1 |
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|
Baseline gout risk factors by baseline anemia status in the ARIC study. |
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|
No anemia |
Anemia |
|
|
|
||
|
Baseline gout risk factors |
N = 9,707 |
N = 1,084 |
|
|
||
|
Male sex, n (%) |
4,315 (44) |
364 (34)** |
|
Mean age, years (SD) |
53.9 (56) |
53.1 (6)** |
|
African American race, n (%) |
1,738 (18) |
549 (51)** |
|
Hypertension, n (%) |
2,878 (30) |
344 (32) |
|
Diuretic use, n (%) |
1,478 (15) |
160 (15) |
|
Diabetes, n (%) |
834 (9) |
94 (9) |
|
Coronary heart disease, n (%) |
304 (3) |
37 (3) |
|
Congestive heart failure, n (%) |
209 (2) |
30 (3) |
|
Mean BMI, kg/m2, (SD) |
27.4 (5) |
27.5 (6) |
|
Mean ethanol intake, grams/week, (SD) |
41.9 (90) |
25.9 (62)** |
|
eGFR, n (%) |
||
|
<60 ml/min/1.73m2 |
186 (2) |
28 (3) |
|
60 to 90 ml/min/1.73m2 |
4,140 (43) |
337 (31) |
|
≥90 ml/min/1.73m2 |
5,381 (55) |
719 (66)** |
|
Education level, n (%) |
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|
<12 years |
1,755 (18) |
274 (25) |
|
12 to 16 years |
4,162 (43) |
418 (39) |
|
17 to 21 years |
3,781 (39) |
388 (36)** |
|
Mean serum uric acid, mg/dL (SD) |
5.9 (2) |
5.7 (2)** |
|
Incident gout, n (%) |
224 (2.3) |
47 (4.3)** |
|
|
||
|
* P-value <0.05 ; ** P-value <0.001 comparing anemia to no anemia. Anemia was defined as hemoglobin <13.5 g/dL for men and <12 g/dL for women. |
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|
McAdams-DeMarco et al. Arthritis Research & Therapy 2012 14:R193 doi:10.1186/ar4026 |
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