Table 2

Fractional clearance of urate (%) in healthy subjects in the morning and afternoon on three separate study days

Subject

Day 1 am

Day 2 am

Day 3 am

Day 1 pm

Day 2 pm

Day 3 pm

Mean


V01

7.8

8.1

8.5

6.8

6.6

7.7

7.6

V02

6.1

8.8

6.9

8.8

11.4

9.7

8.6

V03

9.7

8.1

4.8

8.5

10.4

7.6

8.2

V04

4.2

4.9

4.8

3.4

3.8

4.9

4.4

V05

10.6

7.5

8.1

10.0

9.9

16.5

10.5

V06

8.8

7.6

6.7

7.8

7.9

7.6

7.7

V07

7.3

8.1

11.0

8.5

9.0

10.6

9.1

V08

5.7

5.0

6.3

6.7

5.5

8.0

6.2

V09

5.9

4.3

4.2

6.1

4.2

6.7

5.2

V10

6.4

6.3

7.6

9.5

9.8

9.7

8.2

V11

8.9

9.0

9.8

10.2

8.9

10.0

9.5

V12

6.7

6.5

9.9

7.9

7.9

8.9

8.0

V13

8.7

7.8

6.7

4.8

8.3

7.0

7.2


Mean

7.4

7.1

7.3

7.6

8.0

8.9

7.7


95% CI

6.3 to 8.5

6.2 to 8.0

6.1 to 8.6

6.4 to 8.8

6.5 to 9.4

7.1 to 10.5

6.7 to 8.7


Study 1B; n = 13. Mean age (range) was 35.1 (21 to 73) years.

Kannangara et al. Arthritis Research & Therapy 2012 14:R189   doi:10.1186/ar4020

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