Fractional clearance of urate CU in gouty patients with incrementally increased doses of allopurinol to achieve target concentrations (Study 1D). Mean age (range) was 56 years (17 to 80 years) (n = 22). The number of patients at each dose level is indicated on the graph.
Kannangara et al. Arthritis Research & Therapy 2012 14:R189 doi:10.1186/ar4020