Time to development of manifestations consistent with definite SSc in early SSc and UCTD patients. Percent manifestations of definite SSc, as assessed by routine examinations: skin sclerosis, digital ulcers/scars, two or more teleangectasias, X-ray bibasilar lung fibrosis, X-ray esophageal dysmotility, ECG signs of myocardial fibrosis. Time: five years follow-up. Curves were generated using the Kaplan-Meier method and differences between the two groups were analysed by applying the Log-Rank test. SSc, systemic sclerosis; UCTD, undifferentiated connective tissue disease.
Valentini et al. Arthritis Research & Therapy 2012 14:R188 doi:10.1186/ar4019