Additional file 3.
Figure S3. The effects of simvastatin on cell viability and apoptosis. (A) Effects of simvastatin on the viability of FLSs from an RA patient (patients 1, 2, and 3). Cells were cultured for 24 hours in the presence of TNF-α (20 ng/ml) and simvastatin at different concentrations (10 to 100 μM). Cell viabilities were determined by using MTT assays. (B) Effects of simvastatin on the apoptosis of FLSs, as determined by propidium iodide staining.
Format: TIFF Size: 798KB Download file
Kim et al. Arthritis Research & Therapy 2012 14:R187 doi:10.1186/ar4018