Plasma levels of adrenocorticotropic hormone (ACTH) and cortisol before (gray bars) and after (white bars) 14 days of TNF-α-blocking treatment with etanercept in glucocorticoid-naïve patients with polymyalgia rheumatica (PMR) and in non-PMR control subjects. Box plots show median values and 25% to 75% interquartile ranges. Symbols connected by full lines represent values for individual subjects. Dashed lines represent tendencies between medians of paired data. *P < 0.05; **P < 0.01; ***P < 0.001.
Kreiner and Galbo Arthritis Research & Therapy 2012 14:R186 doi:10.1186/ar4017