Table 1 |
||||
|
Demographic, clinical and biological data of the patients at baseline |
||||
|
Variables |
MTX active (n = 13) (mean ± SD) |
Responders (n = 23) (mean ± SD) |
Non-responders (n = 12) (mean ± SD) |
P-value |
|
|
||||
|
Age (years) |
51.64 ± 10.88 |
50.36 ± 5.82 |
52.25 ± 11.09 |
.762 |
|
Sex (men/women) |
38.46%/61.54% |
33.33%/66.67% |
37.50%/62.50% |
.809 |
|
CRP (mg/dl) |
16.61 ± 7.21 |
14.33 ± 14.10 |
11.68 ± 10.74 |
.569 |
|
Rheumatoid factor (+/-) |
92.30%/7.70 |
80.00%/20.00% |
62.50%/37.50 |
.283 |
|
Anti-CCP (UI/ml) |
423.25 ± 296.01 |
994.60 ± 620.24 |
329.50 ± 7.50 |
.075 |
|
DAS28 |
3.71 ± .71 |
2.64 ± .84 |
3.20 ± .88 |
.090 |
|
Erosions (+/-) |
30.76%/69.24% |
60.00%/40.00% |
71.40%/28.60% |
.518 |
|
Onset of Symptoms (months) |
9.60 ± 9.10 |
100.53 ± 66.14 |
148.14 ± 77.79 |
.090 |
|
HAQ |
.78 ± .53 |
1.18 ± .47 |
1.31 ± .72 |
.553 |
|
|
||||
|
Anti-CCP, anti-cyclic citrullinated peptide antibody; CRP, C-reactive protein; DAS28, Disease Activity Score 28; HAQ, Health Assessment Questionnaire |
||||
|
Chara et al. Arthritis Research & Therapy 2012 14:R175 doi:10.1186/ar3928 |
||||