Table 2

Material sampling and organ involvements in patients with IgG4-RD

Case

Material sampling

Organ involvement

PBMC

CD3/CD20

LSG^a

1

○

○

MD, lymph node, lung

2

○

○

MD, lymph node

3

○

○

MD

4

○

MD, lymph node

5

○

MD, lung

6

○

○

MD, lymph node, para-aorta swelling

7

○

○

Intraorbital mass, retroperitoneal fibrosis

8

○

MD

9

○

MD

10

○

MD

11

○

MD

12

○

MD

13

○

MD

14

○

MD, lung

15

○

MD, liver

PBMCs, peripheral blood mononuclear cells; CD3/CD20, CD3-positive T cells and CD20-positive B cells sorted from PBMCs; LSG, labial salivary gland; MD, Mikulicz disease (salivary and lacrimal glands). ^aAll LSG samples satisfied histopathologic findings of the comprehensive diagnostic criteria for IgG4-related disease (IgG4-RD) 2011.

Tsuboi et al. Arthritis Research & Therapy 2012 14:R171   doi:10.1186/ar3924