Table 3 |
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|
Impact of smoking on positive immune response forpneumococcal serotypes(23F and 6B) in RA patients on methotrexate |
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|
B |
P-value |
Exp(B) |
95% CI |
||
|
|
|||||
|
Lower |
Upper |
||||
|
|
|||||
|
Smoking (pack-years) |
-0.07 |
0.046 |
0.93 |
0.86 |
0.99 |
|
|
|||||
|
Age (years) |
-0.01 |
0.724 |
0.99 |
0.95 |
1.03 |
|
|
|||||
|
Gender |
0.85 |
0.341 |
2.34 |
0.41 |
13.43 |
|
|
|||||
|
CRP |
-0.03 |
0.639 |
0.98 |
0.88 |
1.08 |
|
|
|||||
|
SJC28* |
-0.09 |
0.502 |
0.91 |
0.69 |
1.20 |
|
|
|||||
|
TJC28* |
0.00 |
1.000 |
1.0 |
0.76 |
1.32 |
|
|
|||||
|
Pre-vaccination antibody levels for serotype 23F |
-0.42 |
0.090 |
0.66 |
0.41 |
1.07 |
|
|
|||||
|
Smoking (ever) |
-1.58 |
0.025 |
0.21 |
0.05 |
0.81 |
|
|
|||||
|
*swollen and tender joint count in 28-joint count index Two different logistic regression models were created analyzing smoking (pack-years) and smoking (ever) variable, respectively adjusted for the same covariates. |
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|
Roseman et al. Arthritis Research & Therapy 2012 14:R170 doi:10.1186/ar3923 |
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