Table 3

Site-by-site CT analysis.

Erosion present, number

Erosion absent, number

OR (95%CI)

P

Erosion diameter, in eroded joints, mean (SD)

P

Tophus present, number

Tophus absent, number

OR (95%CI)

P

Tophus diameter, in joints with IO tophus, mean (SD)

P

Spur

Present

127

14

45.1

<0.0001

7.0 (3.7)

<0.0001

121

20

48.4

<0.0001

10.9 (7.9)

0.02

Absent

110

547

(25.0-81.3)

4.5 (3.0)

73

584

(28.4-82.4)

8.2 (6.7)

Osteophyte

Present

116

127

3.3

<0.0001

5.6 (3.2)

0.27

99

144

3.3

<0.0001

8.4 (5.3)

0.006

Absent

121

434

(2.4-4.5)

6.1 (3.9)

95

460

(2.4-4.7)

11.3 (9.1)

Periosteal NBF

Present

41

7

16.6

<0.0001

7.2 (4.4)

0.0005

38

10

14.5

<0.0001

10.4 (7.9)

0.65

Absent

196

554

(7.3-37.5)

5.5 (3.3)

156

594

(7.1-27.0)

9.7 (7.5)

Ankylosis

Present

5

0

26.6

0.002

8.3 (3.1)

0.11

5

0

35.1

0.0008

10.7 (7.3)

0.80

Absent

232

561

(1.5-482.7)

5.8 (3.8)

189

604

(1.9-638.0)

9.8 (7.6)

Sclerosis

Present

179

49

32.3

<0.0001

6.5 (3.8)

<0.0001

161

67

39.1

<0.0001

10.4 (7.9)

0.03

Absent

58

512

(21.3-48.9)

3.9 (2.0)

33

537

(24.9-61.5)

7.3 (4.6)

Relationship of new bone formation (NBF) with erosion and intraosseous tophus on CT (n = 798 joints). CI, confidence interval; CT, computed tomography; OR, odds ratio; SD, standard deviation.

Dalbeth et al. Arthritis Research & Therapy 2012 14:R165   doi:10.1186/ar3913