Figure 8.

Gene expression of IL-1β in PBMCs from gout patients stimulated with MSU and Pam3Cys compared with healthy controls. Measurement of mRNA transcripts of IL-1β after stimulation of PBMCs of patients with gout and controls with FFA C18:0 (A) or Pam₃Cys (B) alone or in combination with monosodium urate (MSU) crystals. Results are shown as ratios with the transcripts of β₂- microglobulin. Gout patients n = 8 and healthy controls n = 6. FFA, free fatty acids; MSU, monosodium urate monohydrate; Pam₃Cys, Pam₃Cys, palmitoyl-3-cystein; PBMC, peripheral blood mononuclear cells.