Two different strategies for articular cartilage repair with PTHrP. Left: recombinant parathyroid hormone-related protein (PTHrP)/peptide can be administered directly or with the aid of biocompatible injectable scaffolds. Right: the PTHrP gene can be delivered by intra-articular injection of gene constructs, or PTHrP-transfected cells alone or combined with injectable scaffolds.
Zhang et al. Arthritis Research & Therapy 2012 14:221 doi:10.1186/ar4025