Table 2

IFN-γ levels in the tuberculosis antigen-stimulated wells and mitogen-stimulated wells that were used as positive controls

RA-TNF1 (n = 38)

RA-TNF2 (n = 38)

TNF-naive RA

(n = 40)

TB

(n = 30)

Leprosy

(n = 23)

Healthy controls (n = 41)


IFN-γ level in tuberulosis antigen well (IU/ml)

3.6 ± 8.4

3.0 ± 6.2

2.8 ± 5

2.3 ± 4.2

7.3 ± 8.0

3.5 ± 6.4

IFN-γ level in positive control well (IU/ml)

7.0 ± 6.4

16.1 ± 14.2a

8.7 ± 6.1

11.6 ± 12.1

12.2 ± 6.1

17.3 ± 6.4


aThe mitogen-nil level increased significantly (P < 0.001) after treatment with TNF-α antagonists.

Hatemi et al. Arthritis Research & Therapy 2012 14:R147   doi:10.1186/ar3882

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