Expression of Semaphorin 3A on CD19+CD25high B cells. (A) demonstrates the MFI of CD19+CD25highSema3A+ expression on B cells in whole blood from SLE patients compared to that of healthy controls (4.27 ± 0.47 versus 2.68 ± 0.09, P = 0.019). (B) is a representative histogram of the lower sema3A expression on B cells from SLE patients compared to that in healthy controls. The blank histogram represents the isotype control. MFI, mean fluorescence intensity; SLE, systemic lupus erythematosis.
Vadasz et al. Arthritis Research & Therapy 2012 14:R146 doi:10.1186/ar3881