Comparison of Nt-proBNP level among groups and correlation with sPAP on transthoracic echocardiography. (A) NT-proBNP levels are significantly higher in the PAH group compared with "at risk," ILD, and control groups. Levels in the at-risk group are significantly higher than those in the control group. (B) NT-proBNP levels have a significant positive correlation with screening sPAP across all groups. NT-proBNP, N-terminal pro-brain natriuretic peptide; PAH, pulmonary arterial hypertension; ILD, interstitial lung disease; sPAP, systolic pulmonary artery pressure on transthoracic echocardiography (mm Hg); log, natural log; r, Pearson coefficient.
Thakkar et al. Arthritis Research & Therapy 2012 14:R143 doi:10.1186/ar3876