Correlation of alkaline phosphatase (AP) staining with inflammatory parameters. (A) Systemic inflammatory parameters: erythrocyte sedimentation rate (ESR) and C reactive protein (CRP). (B) Local inflammatory parameters: synovial concentration of interleukin (IL)-17 and TNF-α; and CCL2 mRNA expression in synovial fluid (SF)-derived cells. Values were correlated using rank correlation and Spearman's coefficient ρ (95% confidence interval for ρ).
Lazić et al. Arthritis Research & Therapy 2012 14:R139 doi:10.1186/ar3872