Table 3

Linear regression analysis for general and RA disease-related characteristics and endothelial function in RA patients from the cross-sectional study

Microvascular function

Macrovascular function

Endothelium-dependent

Endothelium- independent

Endothelium- dependent

Endothelium- independent

RA disease-related characteristics

Disease duration

β = -0.12, P = 0.29

β = 0.21, P = 0.07

β = -0.04 P = 0.76

β = -0.12, P = 0.34

LogCRP

β = -0.61, P = 0.05

β = 0.10, P = 0.32

β = 0.15, P = 0.13

β = 0.00, P = 0.97

LogESR

β = -0.09, P = 0.41

β = 0.18, P = 0.10

β = -0.01, P = 0.95

β = -0.08, P = 0.46

DAS28

β = 0.15, P = 0.15

β = 0.02, P = 0.84

β = 0.06, P = 0.59

β = -0.01, P = 0.93

General characteristics

Age

β = -0.37, R² = 0.135^c

β = -0.20, R² = 0.042^a

β = -0.24, R² = 0.55^a

β = -0.36, R² = 0.126^c

BMI

β = 0.21, P = 0.05

β = 0.08, P = 0.41

β = -0.12, P = 0.26

β = -0.21, P = 0.05

Resting SBP

β = -0.11, P = 0.30

β = -0.02, P = 0.88

β = -0.11, P = 0.27

β = -0.27, R² = 0.066^b

Resting DBP

β = 0.04, P = 0.67

β = 0.08, P = 0.44

β = -0.12, P = 0.25

β = -0.05, P = 0.61

RA disease-related characteristics and general characteristics were entered as independent variables, whereas microvascular and macrovascular endothelial functions were entered as dependent variables in the regression analysis. BMI, body mass index; CRP, C-reactive protein; DAS28, disease activity score in 28 joints; DBP, diastolic blood pressure; ESR, erythrocyte sedimentation rate; SBP, systolic blood pressure. ^aP < 0.05; ^bP < 0.01; ^cP < 0.001. R² value is shown for all significant associations only.

Sandoo et al. Arthritis Research & Therapy 2012 14:R117   doi:10.1186/ar3847