Identified citrullinated peptides at various identification scores. Graph showing the average percentage of all identified peptides that contain at least one citrulline residue at varying identification threshold scores in the synovial fluid of rheumatoid arthritis (RA) patients (black line) and control patients (dashed grey line). Bars indicate the median absolute deviations and asterisks indicate the scores at which a statistically significant difference (P < 0.05) was observed, as determined by a Mann-Whitney test.
Raijmakers et al. Arthritis Research & Therapy 2012 14:R114 doi:10.1186/ar3840