Immunostaining of cartilage from older normal individuals. (A-E) Sections of human femoral condylar cartilage from five non-OA individuals (ages 50 to 68 years), showing detection of neoepitopes generated by collagenases (C1,2C and C2C) and cathepsin K (C2K) in type II collagen. High-magnification views (C and D) were used to better indicate pericellular staining. Bars = 200 μm.
Dejica et al. Arthritis Research & Therapy 2012 14:R113 doi:10.1186/ar3839