Table 1 |
||
|
Characteristics of patients with idiopathic inflammatory myopathies and healthy controls |
||
|
Characteristic |
IIM |
HC |
|
|
||
|
N |
42 |
27 |
|
Age (years) |
53.8 ± 14.2 |
49.5 ± 8.6 |
|
Sex (F/M) |
31/11 |
22/5 |
|
CRP (mg/l) |
9.3 ± 21.6 |
1.8 ± 1.5 |
|
CK (ukat/l, ULN 2.7) |
33.6 ± 58.2 |
NA |
|
Myoglobin (μg/l, ULN 70) |
1345 ± 2422 |
NA |
|
Clinical activity of myositis |
||
|
MYOACT global |
0.15 ± 0.11 |
NA |
|
MMT8 (maximum 80) |
65.34 ± 12.31 |
NA |
|
Autoantibodies (%) |
||
|
Anti-Jo-1 |
24 |
NA |
|
Anti-Ro-52 |
37 |
NA |
|
Anti-Ro-60 |
2 |
NA |
|
Anti-PL-7 |
5 |
NA |
|
Anti-PM-Scl-100 |
12 |
NA |
|
Anti-PM-Scl-75 |
7 |
NA |
|
Anti-Mi-2 |
12 |
NA |
|
Anti-Ku |
2 |
NA |
|
Anti-SRP |
5 |
NA |
|
Anti-U1RNP |
5 |
NA |
|
Anti-histones |
5 |
NA |
|
Other (AMA, M2, CENP-B) |
2 |
NA |
|
Negative |
21 |
NA |
|
Treatment (%) |
||
|
Before therapy |
19 |
0 |
|
Treatment less than 1 month |
53 |
0 |
|
Treatment more than 1 month |
26 |
0 |
|
Glucocorticoids |
67 |
0 |
|
Others |
19 |
0 |
|
|
||
|
Abbreviations: CK, creatine kinase; CRP, C-reactive protein; F, female; HC, healthy controls; IIM, inflammatory myopathies; M, male; MMT8, manual muscle testing of eight muscle groups; MYOACT, disease activity assessment visual analogue scales; N, number; NA, not analysed |
||
|
Filková et al. Arthritis Research & Therapy 2012 14:R111 doi:10.1186/ar3836 |
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