Table 6

Prediction of radiographic damage at 5 years for different cut-off levels of baseline anti-CCP titer

Anti-CCP titer cut-off

Erosions

Larsen score ≥ 15


Sensitivity

Specificity

Accuracy

LR+ve

LR-ve

Sensitivity

Specificity

Accuracy

LR+ve

LR-ve


1

0.80

0.54

0.65

1.7

0.4

0.88

0.52

0.63

1.8

0.2

2

0.59

0.86

0.74

4.2

0.5

0.69

0.82

0.78

3.8

0.4

3

0.56

0.89

0.75

5.0

0.5

0.66

0.85

0.79

4.4

0.4

4

0.54

0.90

0.74

5.3

0.5

0.62

0.86

0.79

4.6

0.4

5

0.53

0.90

0.74

5.2

0.5

0.61

0.86

0.79

4.5

0.5

10

0.50

0.91

0.73

5.5

0.6

0.57

0.87

0.78

4.5

0.5


LR+ve, positive likelihood ratio; LR-ve, negative likelihood ratio.

Burr et al. Arthritis Research & Therapy 2012 14:R109   doi:10.1186/ar3834

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