Table 5

Logistic regression for 5-year radiographic damage according to categories of baseline anti-CCP titer

Anti-CCP titer

Erosions

Larsen score ≥ 15

No with erosions/total in group (%)

OR (95% CI)

P value

Adjusted OR (95% CI)^a

P value^a

No with Larsen ≥ 15/total in group (%)

OR (95% CI)

P value

Adjusted OR (95% CI)^a

P value^a

≤ 2

85/324 (26%)

Ref

-

Ref

-

47/323 (15%)

Ref

-

Ref

-

> 2 to 5

14/25 (56%)

3.6 (1.5, 8.3)

0.003

3.4 (1.2, 9.8)

0.02

11/25 (44%)

4.6 (1.9, 11)

0.0001

4.3 (1.4, 13)

0.009

> 5 to 20

16/22 (73%)

7.5 (2.7, 20)

< 0.0001

3.8 (1.3, 12)

0.02

14/22 (64%)

10.3 (3.9, 27)

< 0.0001

5.3 (1.7, 16)

0.003

> 20

94/116 (81%)

12.4 (6.6, 22)

< 0.0001

9.0

(4.4, 18)

< 0.0001

77/115 (67%)

11.9 (6.7, 21)

< 0.0001

9.7 (4.7, 20)

< 0.0001

^aAdjusted for age, gender, symptom duration and CRP, RF, HAQ, and swollen- and tender-joint counts at baseline. CI, confidence interval; OR, odds ratio.

Burr et al. Arthritis Research & Therapy 2012 14:R109   doi:10.1186/ar3834