Table 4

Logistic regression model exploring association between baseline anti-CCP titer and radiographic and functional outcome at 5 years

5-year outcome

OR (95% CI)

P

Adjusted OR^a

Adjusted P^a

Erosions

1.03 (1.02, 1.04)

< 0.0001

1.03 (1.01, 1.03)

< 0.0001

Larsen score > 15

1.03 (1.02, 1.03)

< 0.0001

1.02 (1.01, 1.03)

< 0.0001

HAQ ≥ 1

1.01 (1.01, 1.02)

< 0.0001

1.00 (0.99, 1.01)

0.47

^aAdjusted for age, gender, symptom duration and CRP, RF, HAQ, and swollen- and tender-joint counts at baseline. OR, odds ratio; CI, confidence interval. Baseline anti-CCP titer was available in 596 patients. ACR, American College of Rheumatology criteria for rheumatoid arthritis; DAS, disease activity score; HAQ, Health Assessment Questionnaire.

Burr et al. Arthritis Research & Therapy 2012 14:R109   doi:10.1186/ar3834