Table 3

Sensitivity, specificity and likelihood ratios for presence of radiographic damage and functional disability at 5 years according to baseline and 5-year autoantibody status

Autoantibody status

Erosions

Larsen score > 15

HAQ ≥ 1


Sensitivity

Specificity

Accuracy

LR

Sensitivity

Specificity

Accuracy

LR

Sensitivity

Specificity

Accuracy

LR


Anti-CCP+

Baseline

0.56

0.89

0.74

5.0

0.65

0.85

0.79

4.3

0.41

0.78

0.61

1.8

Year 5

0.56

0.89

0.75

5.1

0.66

0.86

0.79

4.5

0.41

0.78

0.61

1.8

Base or Year 5

0.59

0.88

0.75

5.1

0.69

0.85

0.79

4.5

0.43

0.77

0.62

1.8

RF+

Baseline

0.44

0.84

0.67

2.8

0.50

0.82

0.71

2.7

0.36

0.77

0.59

1.6

Year 5

0.40

0.84

0.65

2.5

0.42

0.81

0.68

2.2

0.36

0.82

0.61

1.9

Base or Year 5

0.54

0.76

0.67

2.3

0.60

0.74

0.69

2.3

0.45

0.72

0.60

1.6


Logistic regression model; LR, likelihood ratio.

Burr et al. Arthritis Research & Therapy 2012 14:R109   doi:10.1186/ar3834

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