Table 3 |
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|
Sensitivity, specificity and likelihood ratios for presence of radiographic damage and functional disability at 5 years according to baseline and 5-year autoantibody status |
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|
Autoantibody status |
Erosions |
Larsen score > 15 |
HAQ ≥ 1 |
|||||||||
|
|
||||||||||||
|
Sensitivity |
Specificity |
Accuracy |
LR |
Sensitivity |
Specificity |
Accuracy |
LR |
Sensitivity |
Specificity |
Accuracy |
LR |
|
|
|
||||||||||||
|
Anti-CCP+ |
||||||||||||
|
Baseline |
0.56 |
0.89 |
0.74 |
5.0 |
0.65 |
0.85 |
0.79 |
4.3 |
0.41 |
0.78 |
0.61 |
1.8 |
|
Year 5 |
0.56 |
0.89 |
0.75 |
5.1 |
0.66 |
0.86 |
0.79 |
4.5 |
0.41 |
0.78 |
0.61 |
1.8 |
|
Base or Year 5 |
0.59 |
0.88 |
0.75 |
5.1 |
0.69 |
0.85 |
0.79 |
4.5 |
0.43 |
0.77 |
0.62 |
1.8 |
|
RF+ |
||||||||||||
|
Baseline |
0.44 |
0.84 |
0.67 |
2.8 |
0.50 |
0.82 |
0.71 |
2.7 |
0.36 |
0.77 |
0.59 |
1.6 |
|
Year 5 |
0.40 |
0.84 |
0.65 |
2.5 |
0.42 |
0.81 |
0.68 |
2.2 |
0.36 |
0.82 |
0.61 |
1.9 |
|
Base or Year 5 |
0.54 |
0.76 |
0.67 |
2.3 |
0.60 |
0.74 |
0.69 |
2.3 |
0.45 |
0.72 |
0.60 |
1.6 |
|
|
||||||||||||
|
Logistic regression model; LR, likelihood ratio. |
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|
Burr et al. Arthritis Research & Therapy 2012 14:R109 doi:10.1186/ar3834 |
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