Table 1 |
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Baseline characteristics and 5-year outcome of patients who will satisfy cumulatively 1987 ACR criteria for rheumatoid arthritis at any time during the first 5 years of follow-up, versus those who will not |
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Classification |
Satisfying 1987 ACR criteria within the first 5 years (n = 463; 72%) |
NEVER satisfying 1987 ACR criteria within the first 5 years (n = 177; 28%) |
P value |
|
|
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|
Baseline characteristics |
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|
Age (onset) |
55.4 (45.8, 65.4) |
47.7 (34.3, 57.9) |
3.6E-09 |
|
Female |
305 (66%) |
114 (64%) |
0.73 |
|
Symptom duration |
5.3 (2.6, 11.3) |
4.5 (1.9, 9.0) |
0.01 |
|
Anti-CCP +ve |
187 (40.4%) |
8 (4.5%) |
1.2E-18 |
|
Anti-CCP titer |
1.6 (0.7, 42.5) |
0.8 (0.5, 1.4) |
6.4E-16 |
|
HAQ |
0.875 (0.375, 1.5) |
0.25 (0, 0.625) |
5.8E-24 |
|
DAS28 |
4.4 (3.5, 5.4) |
2.8 (2.1, 3.6) |
5.2E-33 |
|
5-year outcome |
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HAQ |
1.125 (0.375, 1.75) |
0.25 (0, 0.625) |
4.1E-24 |
|
DAS28 |
2.8 (2.0, 3.9) |
2.0 (1.15, 2.4) |
1.3E-14 |
|
Erosions |
220 (56.9%) |
12 (8.8%) |
3.1E-22 |
|
Larsen score |
12 (2, 31) |
1 (0, 4) |
9.3E-21 |
|
DMARD received |
278 (60.0%) |
23 (13.1%) |
2.2E-26 |
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Continuous variables expressed as median (interquartile range) and compared by using the Mann-Whitney U test. Categoric variables expressed as number (percentage) and compared by using the χ2 test. ACR, American College of Rheumatology criteria for rheumatoid arthritis; DAS, disease activity score; HAQ, Health Assessment Questionnaire. |
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Burr et al. Arthritis Research & Therapy 2012 14:R109 doi:10.1186/ar3834 |
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