Histograms showing the changes induced by CFA injection into the geriatric knee joint. Volume of synovium (mm3) (A), density of PECAM+ blood vessels (B), but not the density of CD68+ macrophages per unit area (C) were increased 4 weeks after initial CFA injection. Each bar represents the mean ± SEM. *P < 0.05 versus mice that received intraarticular injections of saline as vehicle.
Jimenez-Andrade and Mantyh Arthritis Research & Therapy 2012 14:R101 doi:10.1186/ar3826