Figure 3.

The tissue engineering paradigm. The tissue engineering paradigm consists of isolation and proliferation of a cell source, seeding of the cells onto a scaffold, stimulation of the cell-seeded scaffold to develop a tissue equivalent, and implantation of the construct in vivo. Figure reproduced under a Creative Commons Attribution 3.0 Unported license.

Killian et al. Arthritis Research & Therapy 2012 14:214   doi:10.1186/ar3846
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