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Highly Accessed Review

Recent advances in shoulder research

Megan L Killian, Leonardo Cavinatto, Leesa M Galatz and Stavros Thomopoulos*

Author Affiliations

Department of Orthopaedic Surgery, Washington University, St Louis, MO 63110, USA

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Arthritis Research & Therapy 2012, 14:214  doi:10.1186/ar3846

Published: 15 June 2012

Abstract

Shoulder pathology is a growing concern for the aging population, athletes, and laborers. Shoulder osteoarthritis and rotator cuff disease represent the two most common disorders of the shoulder leading to pain, disability, and degeneration. While research in cartilage regeneration has not yet been translated clinically, the field of shoulder arthroplasty has advanced to the point that joint replacement is an excellent and viable option for a number of pathologic conditions in the shoulder. Rotator cuff disease has been a significant focus of research activity in recent years, as clinicians face the challenge of poor tendon healing and irreversible changes associated with rotator cuff arthropathy. Future treatment modalities involving biologics and tissue engineering hold further promise to improve outcomes for patients suffering from shoulder pathologies.