Optical coherence tomography. Optical coherence tomography (OCT) permits cross-sectional imaging of articular cartilage at resolutions comparable with low-power histology. (a) Arthroscopically firm and surface-intact cartilage shows OCT form birefringence. (b) Loss of birefringent banding on OCT correlates to softened cartilage. (c) Subsurface voids and fissures can be visualized with OCT.
Chu et al. Arthritis Research & Therapy 2012 14:212 doi:10.1186/ar3845