Arthritis Research & Therapy | Volume 14 Issue 3

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Articles

	Volume 14 Issue 3
	Comment
	Editorial Nothing lasts forever - a critical look at sustained remission Daniel Aletaha Arthritis Research & Therapy 2012, 14:116 (9 May 2012) Abstract \| Full text \| PDF \| PubMed
	Editorial Vaccination under TNF blockade - less effective, but worthwhile Martin Aringer Arthritis Research & Therapy 2012, 14:117 (14 May 2012) Abstract \| Full text \| PDF \| PubMed
	Editorial Approaching the immunophysiology of steroid resistance Rick Bucala Arthritis Research & Therapy 2012, 14:118 (18 May 2012) Abstract \| Full text \| PDF \| PubMed
	Editorial The interaction of canonical bone morphogenetic protein- and Wnt-signaling pathways may play an important role in regulating cartilage degradation in osteoarthritis Benjamin Y Chan, Christopher B Little Arthritis Research & Therapy 2012, 14:119 (6 June 2012) Abstract \| Full text \| PDF \| PubMed
	Editorial The LE cell: crime scene or crime stopper? David S Pisetsky Arthritis Research & Therapy 2012, 14:120 (26 June 2012) Abstract \| Full text \| PDF \| PubMed
	Editorial Statins: a revised appraisal for potential additional future treatment indications Robert Weissert Arthritis Research & Therapy 2012, 14:121 (29 June 2012) Abstract \| Full text \| PDF \| PubMed
	Review
	Review The genetics of lupus: a functional perspective Sandra G Guerra, Timothy J Vyse, Deborah S Cunninghame Graham Arthritis Research & Therapy 2012, 14:211 (29 May 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Early diagnosis to enable early treatment of pre-osteoarthritis Constance R Chu, Ashley A Williams, Christian H Coyle, Megan E Bowers Arthritis Research & Therapy 2012, 14:212 (7 June 2012) Abstract \| Full text \| PDF \| PubMed
	Review Recent advances in the diagnosis and treatment of hemophagocytic lymphohistiocytosis Sebastian FN Bode, Kai Lehmberg, Andrea Maul-Pavicic, Thomas Vraetz, Gritta Janka, Udo Stadt, Stephan Ehl Arthritis Research & Therapy 2012, 14:213 (8 June 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Recent advances in shoulder research Megan L Killian, Leonardo Cavinatto, Leesa M Galatz, Stavros Thomopoulos Arthritis Research & Therapy 2012, 14:214 (15 June 2012) Abstract \| Full text \| PDF \| PubMed
	Review Current treatment of hepatitis C-associated rheumatic diseases Clodoveo Ferri, Marco Sebastiani, Alessandro Antonelli, Michele Colaci, A Manfredi, Dilia Giuggioli Arthritis Research & Therapy 2012, 14:215 (25 June 2012) Abstract \| Full text \| PDF \| PubMed
	Review Energy metabolism and rheumatic diseases: from cell to organism Cornelia M Spies, Rainer H Straub, Frank Buttgereit Arthritis Research & Therapy 2012, 14:216 (29 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research
	Research article Inhibition of Th17 differentiation by anti-TNF-alpha therapy in uveitis patients with Behçet's disease Sunao Sugita, Yuko Kawazoe, Ayano Imai, Yukiko Yamada, Shintaro Horie, Manabu Mochizuki Arthritis Research & Therapy 2012, 14:R99 (1 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Anti-type II collagen antibodies are associated with early radiographic destruction in rheumatoid arthritis Mohammed Mullazehi, Marius C Wick, Lars Klareskog, Ronald van Vollenhoven, Johan Rönnelid Arthritis Research & Therapy 2012, 14:R100 (1 May 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Sensory and sympathetic nerve fibers undergo sprouting and neuroma formation in the painful arthritic joint of geriatric mice Juan M Jimenez-Andrade, Patrick W Mantyh Arthritis Research & Therapy 2012, 14:R101 (1 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Levels of adiponectin, a marker for PPAR-gamma activity, correlate with skin fibrosis in systemic sclerosis: potential utility as biomarker? Katja Lakota, Jun Wei, Mary Carns, Monique Hinchcliff, Jungwha Lee, Michael L Whitfield, Snezna Sodin-Semrl, John Varga Arthritis Research & Therapy 2012, 14:R102 (1 May 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article New insights into the role and mechanism of macrophage migration inhibitory factor in steroid-resistant patients with systemic lupus erythematosus Fang-Fang Wang, Li-An Zhu, Yu-Qiong Zou, Hui Zheng, Alisa Wilson, Cheng-De Yang, Nan Shen, Daniel J Wallace, Michael H Weisman, Shun-Le Chen, Liang-Jing Lu Arthritis Research & Therapy 2012, 14:R103 (2 May 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Macrophage migration inhibitory factor (MIF) may play a role in the mechanism of steroid resistance in systemic lupus erythematosus by affecting the NF-κB/IκB signaling cascade, and is a potential therapeutic target.
	Research article PAD4 is not essential for disease in the K/BxN murine autoantibody-mediated model of arthritis Amanda S Rohrbach, Saskia Hemmers, Sanja Arandjelovic, Maripat Corr, Kerri A Mowen Arthritis Research & Therapy 2012, 14:R104 (2 May 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article The effects of oxygen tension and antiaging factor Klotho on Wnt signaling in nucleus pulposus cells Akihiko Hiyama, Fumiyuki Arai, Daisuke Sakai, Katsuya Yokoyama, Joji Mochida Arthritis Research & Therapy 2012, 14:R105 (2 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Efficacy of an immunotoxin to folate receptor beta in the intra-articular treatment of antigen-induced arthritis Taku Nagai, Akira Kyo, Kazuhisa Hasui, Sonshin Takao, Takami Matsuyama Arthritis Research & Therapy 2012, 14:R106 (2 May 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Characterization of inhibitory T cells induced by an analog of type II collagen in an HLA-DR1 humanized mouse model of autoimmune arthritis Masaru Kimata, David L Cullins, Monica L Brown, David D Brand, Edward F Rosloniec, Linda K Myers, John M Stuart, Andrew H Kang Arthritis Research & Therapy 2012, 14:R107 (8 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Osteoporosis in ankylosing spondylitis - prevalence, risk factors and methods of assessment Eva Klingberg, Mattias Lorentzon, Dan Mellström, Mats Geijer, Jan Göthlin, Elisabet Hilme, Martin Hedberg, Hans Carlsten, Helena Forsblad-d'Elia Arthritis Research & Therapy 2012, 14:R108 (8 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Long-term stability of anti-cyclic citrullinated peptide antibody status in patients with early inflammatory polyarthritis Marian L Burr, Sebastien Viatte, Marwan Bukhari, Darren Plant, Deborah P Symmons, Wendy Thomson, Anne Barton Arthritis Research & Therapy 2012, 14:R109 (9 May 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Mycophenolic acid counteracts B cell proliferation and plasmablast formation in patients with systemic lupus erythematosus Sebastian Eickenberg, Eva Mickholz, Elisabeth Jung, Jerzy-Roch Nofer, Herrmann Pavenstädt, Annett M Jacobi Arthritis Research & Therapy 2012, 14:R110 (9 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Resistin in idiopathic inflammatory myopathies Mária Filková, Hana Hulejová, Klára Kuncová, Lenka Pleštilová, Lucie Cerezo, Heřman Mann, Martin Klein, Josef Zámečník, Steffen Gay, Jiří Vencovský, Ladislav Šenolt Arthritis Research & Therapy 2012, 14:R111 (11 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Low-dose oral prednisone improves clinical and ultrasonographic remission rates in early rheumatoid arthritis: results of a 12-month open-label randomised study Carlomaurizio Montecucco, Monica Todoerti, Garifallia Sakellariou, Carlo Scirè, Roberto Caporali Arthritis Research & Therapy 2012, 14:R112 (14 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Increased type II collagen cleavage by cathepsin K and collagenase activities with aging and osteoarthritis in human articular cartilage Valeria M Dejica, John S Mort, Sheila Laverty, John Antoniou, David J Zukor, Michael Tanzer, A Robin Poole Arthritis Research & Therapy 2012, 14:R113 (14 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Elevated levels of fibrinogen-derived endogenous citrullinated peptides in synovial fluid of rheumatoid arthritis patients Reinout Raijmakers, Joyce JBC van Beers, Mahmoud El-Azzouny, Natasja FC Visser, Borut Božič, Ger JM Pruijn, Albert JR Heck Arthritis Research & Therapy 2012, 14:R114 (14 May 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Body mass index influences the response to infliximab in ankylosing spondylitis Sébastien Ottaviani, Yannick Allanore, Florence Tubach, Marine Forien, Anaïs Gardette, Blandine Pasquet, Elisabeth Palazzo, Marine Meunier, Gilles Hayem, Chantal Job-Deslandre, André Kahan, Olivier Meyer, Philippe Dieudé Arthritis Research & Therapy 2012, 14:R115 (14 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article High-density lipoprotein cholesterol subfractions HDL2 and HDL3 are reduced in women with rheumatoid arthritis and may augment the cardiovascular risk of women with RA: a cross-sectional study Elke Arts, Jaap Fransen, Heidi Lemmers, Anton Stalenhoef, Leo Joosten, Piet van Riel, Calin D Popa Arthritis Research & Therapy 2012, 14:R116 (14 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article The role of inflammation and cardiovascular disease risk on microvascular and macrovascular endothelial function in patients with rheumatoid arthritis: a cross-sectional and longitudinal study Aamer Sandoo, George D Kitas, Douglas Carroll, Jet JCS Veldhuijzen van Zanten Arthritis Research & Therapy 2012, 14:R117 (17 May 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles Soi Law, Shayna Street, Chien-Hsiung Yu, Christelle Capini, Sakoontalla Ramnoruth, Hendrik J Nel, Eline van Gorp, Claire Hyde, Kim Lau, Helen Pahau, Anthony W Purcell, Ranjeny Thomas Arthritis Research & Therapy 2012, 14:R118 (17 May 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology
	Research article Serum amyloid A triggers the mosodium urate -mediated mature interleukin-1β production from human synovial fibroblasts Kiyoshi Migita, Tomohiro Koga, Kenshi Satomura, Masahiro Izumi, Takafumi Torigoshi, Yumi Maeda, Yasumori Izumi, Yuka Jiuchi, Taiichiro Miyashita, Satoshi Yamasaki, Yoshihiro Aiba, Atsumasa Komori, Minoru Nakamura, Satoru Motokawa, Atsushi Kawakami, Tadashi Nakamura, Hiromi Ishibashi Arthritis Research & Therapy 2012, 14:R119 (18 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Enhanced susceptibility to lipopolysaccharide-induced arthritis and endotoxin shock in interleukin-32 alpha transgenic mice through induction of tumor necrosis factor alpha Masanori Nakayama, Yasuo Niki, Toshiki Kawasaki, Yuki Takeda, Keisuke Horiuchi, Aya Sasaki, Yasunori Okada, Kazuo Umezawa, Hiroyasu Ikegami, Yoshiaki Toyama, Takeshi Miyamoto Arthritis Research & Therapy 2012, 14:R120 (21 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Limited effect of anti-rheumatic treatment on 15-prostaglandin dehydrogenase in rheumatoid arthritis synovial tissue Karina Gheorghe, Syed Sadique, Patrick Leclerc, Helena Idborg, Ivonne Wobst, Anca Catrina, Per-Johan Jakobsson, Marina Korotkova Arthritis Research & Therapy 2012, 14:R121 (22 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Disruption of rhythms of molecular clocks in primary synovial fibroblasts of patients with osteoarthritis and rheumatoid arthritis, role of IL-1β/TNF Stefanie Haas, Rainer H Straub Arthritis Research & Therapy 2012, 14:R122 (23 May 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Aberrant CD200/CD200R1 expression and function in systemic lupus erythematosus contributes to abnormal T-cell responsiveness and dendritic cell activity Yang Li, Li-dan Zhao, Lu-sha Tong, Su-ning Qian, Yan Ren, Lei Zhang, Xin Ding, Yang Chen, Yan-xia Wang, Wen Zhang, Xiao-feng Zeng, Feng-chun Zhang, Fu-lin Tang, Xuan Zhang, De-nian Ba, Wei He, Xue-tao Cao, Peter E Lipsky Arthritis Research & Therapy 2012, 14:R123 (23 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Can erosions on MRI of the sacroiliac joints be reliably detected in patients with ankylosing spondylitis? - A cross-sectional study Ulrich Weber, Susanne J Pedersen, Mikkel Østergaard, Kaspar Rufibach, Robert GW Lambert, Walter P Maksymowych Arthritis Research & Therapy 2012, 14:R124 (24 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article ERAP1 genetic variations associated with HLA-B27 interaction and disease severity of syndesmophytes formation in Taiwanese ankylosing spondylitis Chin-Man Wang, Huei-Huang Ho, Su-Wei Chang, Yeong-Jian Wu, Jing-Chi Lin, Pi-Yueh Chang, Jianming Wu, Ji-Yih Chen Arthritis Research & Therapy 2012, 14:R125 (25 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Clinicopathologic correlations of renal microthrombosis and inflammatory markers in proliferative lupus nephritis Elena Gonzalo, Oscar Toldos, María P Martínez-Vidal, María C Ordoñez, Begoña Santiago, Antonio Fernández-Nebro, Estíbaliz Loza, Isabel García, Myriam León, José L Pablos, María Galindo Arthritis Research & Therapy 2012, 14:R126 (28 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Association of cytokine and matrix metalloproteinase profiles with disease activity and function in ankylosing spondylitis Derek L Mattey, Jonathan C Packham, Nicola B Nixon, Lucy Coates, Paul Creamer, Sarah Hailwood, Gordon J Taylor, Ashok K Bhalla Arthritis Research & Therapy 2012, 14:R127 (28 May 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article A new immunoprecipitation-real time quantitative PCR assay for anti-Th/To and anti-U3RNP antibody detection in systemic sclerosis Angela Ceribelli, Minoru Satoh, Edward KL Chan Arthritis Research & Therapy 2012, 14:R128 (29 May 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Defining cut-off values for disease activity states and improvement scores for patient-reported outcomes: the example of the Rheumatoid Arthritis Impact of Disease (RAID) Maxime Dougados, Yves Brault, Isabelle Logeart, Désirée van der Heijde, Laure Gossec, Tore Kvien Arthritis Research & Therapy 2012, 14:R129 (30 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Treatment with the arginase inhibitor N_w-hydroxy-nor-L-arginine restores endothelial function in rat adjuvant-induced arthritis Clément Prati, Alain Berthelot, Bernadette Kantelip, Daniel Wendling, Céline Demougeot Arthritis Research & Therapy 2012, 14:R130 (30 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Evaluating joint-space narrowing and cartilage loss in rheumatoid arthritis by using MRI Charles G Peterfy, Julie C DiCarlo, Ewa Olech, Maire-Agnes Bagnard, Annarita Gabriele, Norman Gaylis Arthritis Research & Therapy 2012, 14:R131 (30 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article The relationship between hand osteoarthritis and serum leptin concentration in participants of the Third National Health and Nutrition Examination Survey Mei Massengale, William M Reichmann, Elena Losina, Daniel H Solomon, Jeffrey N Katz Arthritis Research & Therapy 2012, 14:R132 (31 May 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Upregulation of tumor necrosis factor receptor-associated factor 6 correlated with synovitis severity in rheumatoid arthritis Lang-Jing Zhu, Lie Dai, Dong-Hui Zheng, Ying-Qian Mo, Xia Ou-Yang, Xiu-Ning Wei, Jun Shen, Bai-Yu Zhang Arthritis Research & Therapy 2012, 14:R133 (4 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Establishment and characterization of a sustained delayed-type hypersensitivity model with arthritic manifestations in C57BL/6J mice Sara M Atkinson, Pernille A Usher, Peter H Kvist, Helle Markholst, Claus Haase, Anneline Nansen Arthritis Research & Therapy 2012, 14:R134 (7 June 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The delayed-type hypersensitivity arthritis model shares features with human rheumatoid arthritis and the collagen-induced arthritis model, and may have potential for the preclinical screening of novel drugs against rheumatoid arthritis.
	Research article Hydroxychloroquine improves insulin sensitivity in obese non-diabetic individuals Emileigh Mercer, Laura Rekedal, Rajesh Garg, Bing Lu, Elena M Massarotti, Daniel H Solomon Arthritis Research & Therapy 2012, 14:R135 (7 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Properties and usefulness of aggregates of synovial mesenchymal stem cells as a source for cartilage regeneration Shiro Suzuki, Takeshi Muneta, Kunikazu Tsuji, Shizuko Ichinose, Hatsune Makino, Akihiro Umezawa, Ichiro Sekiya Arthritis Research & Therapy 2012, 14:R136 (7 June 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Aggregated mesenchymal stem cells are a useful source for cartilage regeneration, as they are easy to prepare, have high chondrogenic potential and attach efficiently.
	Research article Interleukin-7-aggravated joint inflammation and tissue destruction in collagen-induced arthritis is associated with T-cell and B-cell activation Sarita AY Hartgring, Cynthia R Willis, Johannes WJ Bijlsma, Floris PJG Lafeber, Joel AG van Roon Arthritis Research & Therapy 2012, 14:R137 (7 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Adenosine receptor expression in rheumatoid synovium: a basis for methotrexate action Lisa K Stamp, Jody Hazlett, Rebecca L Roberts, Christopher Frampton, John Highton, Paul A Hessian Arthritis Research & Therapy 2012, 14:R138 (8 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Osteoblastogenesis from synovial fluid-derived cells is related to the type and severity of juvenile idiopathic arthritis Elvira Lazić, Marija Jelušić, Danka Grčević, Ana Marušić, Nataša Kovačić Arthritis Research & Therapy 2012, 14:R139 (12 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article C5a and its receptors in human anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis Jun Yuan, Shen-Ju Gou, Jing Huang, Jian Hao, Min Chen, Ming-Hui Zhao Arthritis Research & Therapy 2012, 14:R140 (12 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Anti-tumor necrosis factor therapy improves insulin resistance, beta cell function and insulin signaling in active rheumatoid arthritis patients with high insulin resistance Ilias Stagakis, George Bertsias, Stylianos Karvounaris, Melina Kavousanaki, Dimitra Virla, Amalia Raptopoulou, Dimitrios Kardassis, Dimitrios T Boumpas, Prodromos I Sidiropoulos Arthritis Research & Therapy 2012, 14:R141 (12 June 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Twelve weeks of anti-tumor necrosis factor (TNF) therapy improved insulin sensitivity, beta cell function and insulin signaling in active rheumatoid arthritis patients with high insulin resistance.
	Research article Investigation of the role of endosomal Toll-like receptors in murine collagen-induced arthritis reveals a potential role for TLR7 in disease maintenance Saba Alzabin, Philip Kong, Mino Medghalchi, Andrew Palfreeman, Richard Williams, Sandra Sacre Arthritis Research & Therapy 2012, 14:R142 (12 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article N-terminal pro-brain natriuretic peptide in a novel screening algorithm for pulmonary arterial hypertension in systemic sclerosis: a case-control study Vivek Thakkar, Wendy M Stevens, David Prior, Owen A Moore, Jillian Byron, Danny Liew, Karen Patterson, Pravin Hissaria, Janet Roddy, Jane Zochling, Joanne Sahhar, Peter Nash, Kathleen Tymms, David Celermajer, Eli Gabbay, Peter Youssef, Susanna M Proudman, Mandana Nikpour Arthritis Research & Therapy 2012, 14:R143 (12 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article CD109, a TGF-β co-receptor, attenuates extracellular matrix production in scleroderma skin fibroblasts Xiao-Yong Man, Kenneth W Finnson, Murray Baron, Anie Philip Arthritis Research & Therapy 2012, 14:R144 (13 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article B-cell depletion therapy in patients with diffuse systemic sclerosis associates with a significant decrease in PDGFR expression and activation in spindle-like cells in the skin Dimitrios Daoussis, Athanassios C Tsamandas, Stamatis-Nick C Liossis, Ioannis Antonopoulos, Elli Karatza, Georgios Yiannopoulos, Andrew P Andonopoulos Arthritis Research & Therapy 2012, 14:R145 (14 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Semaphorin 3A is a marker for disease activity and a potential immunoregulator in systemic lupus erythematosus Zahava Vadasz, Tharwat Haj, Katalin Halasz, Itzhak Rosner, Gleb Slobodin, Dina Attias, Aharon Kessel, Ofra Kessler, Gera Neufeld, Elias Toubi Arthritis Research & Therapy 2012, 14:R146 (14 June 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Quantiferon-TB Gold in tube assay for the screening of tuberculosis before and during treatment with tumor necrosis factor alpha antagonists Gulen Hatemi, Melike Melikoglu, Fatma Ozbakir, Koray Tascilar, Hasan Yazici Arthritis Research & Therapy 2012, 14:R147 (18 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Exercise training in pulmonary arterial hypertension associated with connective tissue diseases Ekkehard Grünig, Felicitas Maier, Nicola Ehlken, Christine Fischer, Mona Lichtblau, Norbert Blank, Christoph Fiehn, Frank Stöckl, Felix Prange, Gerd Staehler, Frank Reichenberger, Henning Tiede, Michael Halank, Hans-Jürgen Seyfarth, Simone Wagner, Christian Nagel Arthritis Research & Therapy 2012, 14:R148 (18 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article RANKL synthesized by articular chondrocytes contributes to juxta-articular bone loss in chronic arthritis Maria J Martínez-Calatrava, Ivan Prieto-Potín, Jorge A Roman-Blas, Lidia Tardio, Raquel Largo, Gabriel Herrero-Beaumont Arthritis Research & Therapy 2012, 14:R149 (18 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Nafamostat mesylate, a serine protease inhibitor, demonstrates novel antimicrobial properties and effectiveness in Chlamydia-induced arthritis Robert D Inman, Basil Chiu Arthritis Research & Therapy 2012, 14:R150 (20 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Hyaluronan injection in murine osteoarthritis prevents TGFbeta 1-induced synovial neovascularization and fibrosis and maintains articular cartilage integrity by a CD44-dependent mechanism Jun Li, Daniel J Gorski, Wendy Anemaet, Jennifer Velasco, Jun Takeuchi, John D Sandy, Anna Plaas Arthritis Research & Therapy 2012, 14:R151 (21 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Aldolase predicts subsequent myopathy occurrence in systemic sclerosis Cécile Tolédano, Murielle Gain, Adrien Kettaneh, Bruno Baudin, Catherine Johanet, Patrick Chérin, Sébastien Rivière, Jean Cabane, Kiet Tiev Arthritis Research & Therapy 2012, 14:R152 (22 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Decreased hypertrophic differentiation accompanies enhanced matrix formation in co-cultures of outer meniscus cells with bone marrow mesenchymal stromal cells David JJ Saliken, Aillette Mulet-Sierra, Nadr M Jomha, Adetola B Adesida Arthritis Research & Therapy 2012, 14:R153 (22 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Analysis of the association between CD40 and CD40 ligand polymorphisms and systemic sclerosis María Teruel, Carmen P Simeon, Jasper Broen, Madelon C Vonk, Patricia Carreira, Maria Camps, Rosa García-Portales, Esmeralda Delgado-Frías, Maria Gallego, Gerard Espinosa, the Spanish Scleroderma Group, Lorenzo Beretta, Paolo Airó, Claudio Lunardi, Gabriela Riemekasten, Torsten Witte, Thomas Krieg, Alexander Kreuter, Jörg HW Distler, Nicolas Hunzelmann, Bobby P Koeleman, Alexandre E Voskuyl, Annemie J Schuerwegh, Miguel González-Gay, Timothy RDJ Radstake, Javier Martin Arthritis Research & Therapy 2012, 14:R154 (25 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Hydroxychloroquine is associated with impaired interferon-alpha and tumor necrosis factor-alpha production by plasmacytoid dendritic cells in systemic lupus erythematosus Karim Sacre, Lindsey A Criswell, Joseph M McCune Arthritis Research & Therapy 2012, 14:R155 (27 June 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Validation of ACR/EULAR definition of remission in rheumatoid arthritis from RA practice: the ESPOIR cohort Bin Zhang, Bernard Combe, Nathalie Rincheval, David T Felson Arthritis Research & Therapy 2012, 14:R156 (29 June 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Correspondence
	Letter Response to 'Adiponectin associates with markers of cartilage degradation in osteoarthritis and induces production of proinflammatory and catabolic factors through mitogen-activated protein kinase pathways' Cengiz Korkmaz Arthritis Research & Therapy 2012, 14:402 (21 June 2012) Abstract \| Full text \| PDF \| PubMed

	Volume 14 Issue 3
	Comment
	Editorial Nothing lasts forever - a critical look at sustained remission Daniel Aletaha Arthritis Research & Therapy 2012, 14:116 (9 May 2012) Abstract \| Full text \| PDF \| PubMed
	Editorial Vaccination under TNF blockade - less effective, but worthwhile Martin Aringer Arthritis Research & Therapy 2012, 14:117 (14 May 2012) Abstract \| Full text \| PDF \| PubMed
	Editorial Approaching the immunophysiology of steroid resistance Rick Bucala Arthritis Research & Therapy 2012, 14:118 (18 May 2012) Abstract \| Full text \| PDF \| PubMed
	Editorial The interaction of canonical bone morphogenetic protein- and Wnt-signaling pathways may play an important role in regulating cartilage degradation in osteoarthritis Benjamin Y Chan, Christopher B Little Arthritis Research & Therapy 2012, 14:119 (6 June 2012) Abstract \| Full text \| PDF \| PubMed
	Editorial The LE cell: crime scene or crime stopper? David S Pisetsky Arthritis Research & Therapy 2012, 14:120 (26 June 2012) Abstract \| Full text \| PDF \| PubMed
	Editorial Statins: a revised appraisal for potential additional future treatment indications Robert Weissert Arthritis Research & Therapy 2012, 14:121 (29 June 2012) Abstract \| Full text \| PDF \| PubMed
	Review
	Review The genetics of lupus: a functional perspective Sandra G Guerra, Timothy J Vyse, Deborah S Cunninghame Graham Arthritis Research & Therapy 2012, 14:211 (29 May 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Early diagnosis to enable early treatment of pre-osteoarthritis Constance R Chu, Ashley A Williams, Christian H Coyle, Megan E Bowers Arthritis Research & Therapy 2012, 14:212 (7 June 2012) Abstract \| Full text \| PDF \| PubMed
	Review Recent advances in the diagnosis and treatment of hemophagocytic lymphohistiocytosis Sebastian FN Bode, Kai Lehmberg, Andrea Maul-Pavicic, Thomas Vraetz, Gritta Janka, Udo Stadt, Stephan Ehl Arthritis Research & Therapy 2012, 14:213 (8 June 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Recent advances in shoulder research Megan L Killian, Leonardo Cavinatto, Leesa M Galatz, Stavros Thomopoulos Arthritis Research & Therapy 2012, 14:214 (15 June 2012) Abstract \| Full text \| PDF \| PubMed
	Review Current treatment of hepatitis C-associated rheumatic diseases Clodoveo Ferri, Marco Sebastiani, Alessandro Antonelli, Michele Colaci, A Manfredi, Dilia Giuggioli Arthritis Research & Therapy 2012, 14:215 (25 June 2012) Abstract \| Full text \| PDF \| PubMed
	Review Energy metabolism and rheumatic diseases: from cell to organism Cornelia M Spies, Rainer H Straub, Frank Buttgereit Arthritis Research & Therapy 2012, 14:216 (29 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research
	Research article Inhibition of Th17 differentiation by anti-TNF-alpha therapy in uveitis patients with Behçet's disease Sunao Sugita, Yuko Kawazoe, Ayano Imai, Yukiko Yamada, Shintaro Horie, Manabu Mochizuki Arthritis Research & Therapy 2012, 14:R99 (1 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Anti-type II collagen antibodies are associated with early radiographic destruction in rheumatoid arthritis Mohammed Mullazehi, Marius C Wick, Lars Klareskog, Ronald van Vollenhoven, Johan Rönnelid Arthritis Research & Therapy 2012, 14:R100 (1 May 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Sensory and sympathetic nerve fibers undergo sprouting and neuroma formation in the painful arthritic joint of geriatric mice Juan M Jimenez-Andrade, Patrick W Mantyh Arthritis Research & Therapy 2012, 14:R101 (1 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Levels of adiponectin, a marker for PPAR-gamma activity, correlate with skin fibrosis in systemic sclerosis: potential utility as biomarker? Katja Lakota, Jun Wei, Mary Carns, Monique Hinchcliff, Jungwha Lee, Michael L Whitfield, Snezna Sodin-Semrl, John Varga Arthritis Research & Therapy 2012, 14:R102 (1 May 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article New insights into the role and mechanism of macrophage migration inhibitory factor in steroid-resistant patients with systemic lupus erythematosus Fang-Fang Wang, Li-An Zhu, Yu-Qiong Zou, Hui Zheng, Alisa Wilson, Cheng-De Yang, Nan Shen, Daniel J Wallace, Michael H Weisman, Shun-Le Chen, Liang-Jing Lu Arthritis Research & Therapy 2012, 14:R103 (2 May 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Macrophage migration inhibitory factor (MIF) may play a role in the mechanism of steroid resistance in systemic lupus erythematosus by affecting the NF-κB/IκB signaling cascade, and is a potential therapeutic target.
	Research article PAD4 is not essential for disease in the K/BxN murine autoantibody-mediated model of arthritis Amanda S Rohrbach, Saskia Hemmers, Sanja Arandjelovic, Maripat Corr, Kerri A Mowen Arthritis Research & Therapy 2012, 14:R104 (2 May 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article The effects of oxygen tension and antiaging factor Klotho on Wnt signaling in nucleus pulposus cells Akihiko Hiyama, Fumiyuki Arai, Daisuke Sakai, Katsuya Yokoyama, Joji Mochida Arthritis Research & Therapy 2012, 14:R105 (2 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Efficacy of an immunotoxin to folate receptor beta in the intra-articular treatment of antigen-induced arthritis Taku Nagai, Akira Kyo, Kazuhisa Hasui, Sonshin Takao, Takami Matsuyama Arthritis Research & Therapy 2012, 14:R106 (2 May 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Characterization of inhibitory T cells induced by an analog of type II collagen in an HLA-DR1 humanized mouse model of autoimmune arthritis Masaru Kimata, David L Cullins, Monica L Brown, David D Brand, Edward F Rosloniec, Linda K Myers, John M Stuart, Andrew H Kang Arthritis Research & Therapy 2012, 14:R107 (8 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Osteoporosis in ankylosing spondylitis - prevalence, risk factors and methods of assessment Eva Klingberg, Mattias Lorentzon, Dan Mellström, Mats Geijer, Jan Göthlin, Elisabet Hilme, Martin Hedberg, Hans Carlsten, Helena Forsblad-d'Elia Arthritis Research & Therapy 2012, 14:R108 (8 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Long-term stability of anti-cyclic citrullinated peptide antibody status in patients with early inflammatory polyarthritis Marian L Burr, Sebastien Viatte, Marwan Bukhari, Darren Plant, Deborah P Symmons, Wendy Thomson, Anne Barton Arthritis Research & Therapy 2012, 14:R109 (9 May 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Mycophenolic acid counteracts B cell proliferation and plasmablast formation in patients with systemic lupus erythematosus Sebastian Eickenberg, Eva Mickholz, Elisabeth Jung, Jerzy-Roch Nofer, Herrmann Pavenstädt, Annett M Jacobi Arthritis Research & Therapy 2012, 14:R110 (9 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Resistin in idiopathic inflammatory myopathies Mária Filková, Hana Hulejová, Klára Kuncová, Lenka Pleštilová, Lucie Cerezo, Heřman Mann, Martin Klein, Josef Zámečník, Steffen Gay, Jiří Vencovský, Ladislav Šenolt Arthritis Research & Therapy 2012, 14:R111 (11 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Low-dose oral prednisone improves clinical and ultrasonographic remission rates in early rheumatoid arthritis: results of a 12-month open-label randomised study Carlomaurizio Montecucco, Monica Todoerti, Garifallia Sakellariou, Carlo Scirè, Roberto Caporali Arthritis Research & Therapy 2012, 14:R112 (14 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Increased type II collagen cleavage by cathepsin K and collagenase activities with aging and osteoarthritis in human articular cartilage Valeria M Dejica, John S Mort, Sheila Laverty, John Antoniou, David J Zukor, Michael Tanzer, A Robin Poole Arthritis Research & Therapy 2012, 14:R113 (14 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Elevated levels of fibrinogen-derived endogenous citrullinated peptides in synovial fluid of rheumatoid arthritis patients Reinout Raijmakers, Joyce JBC van Beers, Mahmoud El-Azzouny, Natasja FC Visser, Borut Božič, Ger JM Pruijn, Albert JR Heck Arthritis Research & Therapy 2012, 14:R114 (14 May 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Body mass index influences the response to infliximab in ankylosing spondylitis Sébastien Ottaviani, Yannick Allanore, Florence Tubach, Marine Forien, Anaïs Gardette, Blandine Pasquet, Elisabeth Palazzo, Marine Meunier, Gilles Hayem, Chantal Job-Deslandre, André Kahan, Olivier Meyer, Philippe Dieudé Arthritis Research & Therapy 2012, 14:R115 (14 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article High-density lipoprotein cholesterol subfractions HDL2 and HDL3 are reduced in women with rheumatoid arthritis and may augment the cardiovascular risk of women with RA: a cross-sectional study Elke Arts, Jaap Fransen, Heidi Lemmers, Anton Stalenhoef, Leo Joosten, Piet van Riel, Calin D Popa Arthritis Research & Therapy 2012, 14:R116 (14 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article The role of inflammation and cardiovascular disease risk on microvascular and macrovascular endothelial function in patients with rheumatoid arthritis: a cross-sectional and longitudinal study Aamer Sandoo, George D Kitas, Douglas Carroll, Jet JCS Veldhuijzen van Zanten Arthritis Research & Therapy 2012, 14:R117 (17 May 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles Soi Law, Shayna Street, Chien-Hsiung Yu, Christelle Capini, Sakoontalla Ramnoruth, Hendrik J Nel, Eline van Gorp, Claire Hyde, Kim Lau, Helen Pahau, Anthony W Purcell, Ranjeny Thomas Arthritis Research & Therapy 2012, 14:R118 (17 May 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology
	Research article Serum amyloid A triggers the mosodium urate -mediated mature interleukin-1β production from human synovial fibroblasts Kiyoshi Migita, Tomohiro Koga, Kenshi Satomura, Masahiro Izumi, Takafumi Torigoshi, Yumi Maeda, Yasumori Izumi, Yuka Jiuchi, Taiichiro Miyashita, Satoshi Yamasaki, Yoshihiro Aiba, Atsumasa Komori, Minoru Nakamura, Satoru Motokawa, Atsushi Kawakami, Tadashi Nakamura, Hiromi Ishibashi Arthritis Research & Therapy 2012, 14:R119 (18 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Enhanced susceptibility to lipopolysaccharide-induced arthritis and endotoxin shock in interleukin-32 alpha transgenic mice through induction of tumor necrosis factor alpha Masanori Nakayama, Yasuo Niki, Toshiki Kawasaki, Yuki Takeda, Keisuke Horiuchi, Aya Sasaki, Yasunori Okada, Kazuo Umezawa, Hiroyasu Ikegami, Yoshiaki Toyama, Takeshi Miyamoto Arthritis Research & Therapy 2012, 14:R120 (21 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Limited effect of anti-rheumatic treatment on 15-prostaglandin dehydrogenase in rheumatoid arthritis synovial tissue Karina Gheorghe, Syed Sadique, Patrick Leclerc, Helena Idborg, Ivonne Wobst, Anca Catrina, Per-Johan Jakobsson, Marina Korotkova Arthritis Research & Therapy 2012, 14:R121 (22 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Disruption of rhythms of molecular clocks in primary synovial fibroblasts of patients with osteoarthritis and rheumatoid arthritis, role of IL-1β/TNF Stefanie Haas, Rainer H Straub Arthritis Research & Therapy 2012, 14:R122 (23 May 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Aberrant CD200/CD200R1 expression and function in systemic lupus erythematosus contributes to abnormal T-cell responsiveness and dendritic cell activity Yang Li, Li-dan Zhao, Lu-sha Tong, Su-ning Qian, Yan Ren, Lei Zhang, Xin Ding, Yang Chen, Yan-xia Wang, Wen Zhang, Xiao-feng Zeng, Feng-chun Zhang, Fu-lin Tang, Xuan Zhang, De-nian Ba, Wei He, Xue-tao Cao, Peter E Lipsky Arthritis Research & Therapy 2012, 14:R123 (23 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Can erosions on MRI of the sacroiliac joints be reliably detected in patients with ankylosing spondylitis? - A cross-sectional study Ulrich Weber, Susanne J Pedersen, Mikkel Østergaard, Kaspar Rufibach, Robert GW Lambert, Walter P Maksymowych Arthritis Research & Therapy 2012, 14:R124 (24 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article ERAP1 genetic variations associated with HLA-B27 interaction and disease severity of syndesmophytes formation in Taiwanese ankylosing spondylitis Chin-Man Wang, Huei-Huang Ho, Su-Wei Chang, Yeong-Jian Wu, Jing-Chi Lin, Pi-Yueh Chang, Jianming Wu, Ji-Yih Chen Arthritis Research & Therapy 2012, 14:R125 (25 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Clinicopathologic correlations of renal microthrombosis and inflammatory markers in proliferative lupus nephritis Elena Gonzalo, Oscar Toldos, María P Martínez-Vidal, María C Ordoñez, Begoña Santiago, Antonio Fernández-Nebro, Estíbaliz Loza, Isabel García, Myriam León, José L Pablos, María Galindo Arthritis Research & Therapy 2012, 14:R126 (28 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Association of cytokine and matrix metalloproteinase profiles with disease activity and function in ankylosing spondylitis Derek L Mattey, Jonathan C Packham, Nicola B Nixon, Lucy Coates, Paul Creamer, Sarah Hailwood, Gordon J Taylor, Ashok K Bhalla Arthritis Research & Therapy 2012, 14:R127 (28 May 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article A new immunoprecipitation-real time quantitative PCR assay for anti-Th/To and anti-U3RNP antibody detection in systemic sclerosis Angela Ceribelli, Minoru Satoh, Edward KL Chan Arthritis Research & Therapy 2012, 14:R128 (29 May 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Defining cut-off values for disease activity states and improvement scores for patient-reported outcomes: the example of the Rheumatoid Arthritis Impact of Disease (RAID) Maxime Dougados, Yves Brault, Isabelle Logeart, Désirée van der Heijde, Laure Gossec, Tore Kvien Arthritis Research & Therapy 2012, 14:R129 (30 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Treatment with the arginase inhibitor N_w-hydroxy-nor-L-arginine restores endothelial function in rat adjuvant-induced arthritis Clément Prati, Alain Berthelot, Bernadette Kantelip, Daniel Wendling, Céline Demougeot Arthritis Research & Therapy 2012, 14:R130 (30 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Evaluating joint-space narrowing and cartilage loss in rheumatoid arthritis by using MRI Charles G Peterfy, Julie C DiCarlo, Ewa Olech, Maire-Agnes Bagnard, Annarita Gabriele, Norman Gaylis Arthritis Research & Therapy 2012, 14:R131 (30 May 2012) Abstract \| Full text \| PDF \| PubMed
	Research article The relationship between hand osteoarthritis and serum leptin concentration in participants of the Third National Health and Nutrition Examination Survey Mei Massengale, William M Reichmann, Elena Losina, Daniel H Solomon, Jeffrey N Katz Arthritis Research & Therapy 2012, 14:R132 (31 May 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Upregulation of tumor necrosis factor receptor-associated factor 6 correlated with synovitis severity in rheumatoid arthritis Lang-Jing Zhu, Lie Dai, Dong-Hui Zheng, Ying-Qian Mo, Xia Ou-Yang, Xiu-Ning Wei, Jun Shen, Bai-Yu Zhang Arthritis Research & Therapy 2012, 14:R133 (4 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Establishment and characterization of a sustained delayed-type hypersensitivity model with arthritic manifestations in C57BL/6J mice Sara M Atkinson, Pernille A Usher, Peter H Kvist, Helle Markholst, Claus Haase, Anneline Nansen Arthritis Research & Therapy 2012, 14:R134 (7 June 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The delayed-type hypersensitivity arthritis model shares features with human rheumatoid arthritis and the collagen-induced arthritis model, and may have potential for the preclinical screening of novel drugs against rheumatoid arthritis.
	Research article Hydroxychloroquine improves insulin sensitivity in obese non-diabetic individuals Emileigh Mercer, Laura Rekedal, Rajesh Garg, Bing Lu, Elena M Massarotti, Daniel H Solomon Arthritis Research & Therapy 2012, 14:R135 (7 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Properties and usefulness of aggregates of synovial mesenchymal stem cells as a source for cartilage regeneration Shiro Suzuki, Takeshi Muneta, Kunikazu Tsuji, Shizuko Ichinose, Hatsune Makino, Akihiro Umezawa, Ichiro Sekiya Arthritis Research & Therapy 2012, 14:R136 (7 June 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Aggregated mesenchymal stem cells are a useful source for cartilage regeneration, as they are easy to prepare, have high chondrogenic potential and attach efficiently.
	Research article Interleukin-7-aggravated joint inflammation and tissue destruction in collagen-induced arthritis is associated with T-cell and B-cell activation Sarita AY Hartgring, Cynthia R Willis, Johannes WJ Bijlsma, Floris PJG Lafeber, Joel AG van Roon Arthritis Research & Therapy 2012, 14:R137 (7 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Adenosine receptor expression in rheumatoid synovium: a basis for methotrexate action Lisa K Stamp, Jody Hazlett, Rebecca L Roberts, Christopher Frampton, John Highton, Paul A Hessian Arthritis Research & Therapy 2012, 14:R138 (8 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Osteoblastogenesis from synovial fluid-derived cells is related to the type and severity of juvenile idiopathic arthritis Elvira Lazić, Marija Jelušić, Danka Grčević, Ana Marušić, Nataša Kovačić Arthritis Research & Therapy 2012, 14:R139 (12 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article C5a and its receptors in human anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis Jun Yuan, Shen-Ju Gou, Jing Huang, Jian Hao, Min Chen, Ming-Hui Zhao Arthritis Research & Therapy 2012, 14:R140 (12 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Anti-tumor necrosis factor therapy improves insulin resistance, beta cell function and insulin signaling in active rheumatoid arthritis patients with high insulin resistance Ilias Stagakis, George Bertsias, Stylianos Karvounaris, Melina Kavousanaki, Dimitra Virla, Amalia Raptopoulou, Dimitrios Kardassis, Dimitrios T Boumpas, Prodromos I Sidiropoulos Arthritis Research & Therapy 2012, 14:R141 (12 June 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Twelve weeks of anti-tumor necrosis factor (TNF) therapy improved insulin sensitivity, beta cell function and insulin signaling in active rheumatoid arthritis patients with high insulin resistance.
	Research article Investigation of the role of endosomal Toll-like receptors in murine collagen-induced arthritis reveals a potential role for TLR7 in disease maintenance Saba Alzabin, Philip Kong, Mino Medghalchi, Andrew Palfreeman, Richard Williams, Sandra Sacre Arthritis Research & Therapy 2012, 14:R142 (12 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article N-terminal pro-brain natriuretic peptide in a novel screening algorithm for pulmonary arterial hypertension in systemic sclerosis: a case-control study Vivek Thakkar, Wendy M Stevens, David Prior, Owen A Moore, Jillian Byron, Danny Liew, Karen Patterson, Pravin Hissaria, Janet Roddy, Jane Zochling, Joanne Sahhar, Peter Nash, Kathleen Tymms, David Celermajer, Eli Gabbay, Peter Youssef, Susanna M Proudman, Mandana Nikpour Arthritis Research & Therapy 2012, 14:R143 (12 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article CD109, a TGF-β co-receptor, attenuates extracellular matrix production in scleroderma skin fibroblasts Xiao-Yong Man, Kenneth W Finnson, Murray Baron, Anie Philip Arthritis Research & Therapy 2012, 14:R144 (13 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article B-cell depletion therapy in patients with diffuse systemic sclerosis associates with a significant decrease in PDGFR expression and activation in spindle-like cells in the skin Dimitrios Daoussis, Athanassios C Tsamandas, Stamatis-Nick C Liossis, Ioannis Antonopoulos, Elli Karatza, Georgios Yiannopoulos, Andrew P Andonopoulos Arthritis Research & Therapy 2012, 14:R145 (14 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Semaphorin 3A is a marker for disease activity and a potential immunoregulator in systemic lupus erythematosus Zahava Vadasz, Tharwat Haj, Katalin Halasz, Itzhak Rosner, Gleb Slobodin, Dina Attias, Aharon Kessel, Ofra Kessler, Gera Neufeld, Elias Toubi Arthritis Research & Therapy 2012, 14:R146 (14 June 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Quantiferon-TB Gold in tube assay for the screening of tuberculosis before and during treatment with tumor necrosis factor alpha antagonists Gulen Hatemi, Melike Melikoglu, Fatma Ozbakir, Koray Tascilar, Hasan Yazici Arthritis Research & Therapy 2012, 14:R147 (18 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Exercise training in pulmonary arterial hypertension associated with connective tissue diseases Ekkehard Grünig, Felicitas Maier, Nicola Ehlken, Christine Fischer, Mona Lichtblau, Norbert Blank, Christoph Fiehn, Frank Stöckl, Felix Prange, Gerd Staehler, Frank Reichenberger, Henning Tiede, Michael Halank, Hans-Jürgen Seyfarth, Simone Wagner, Christian Nagel Arthritis Research & Therapy 2012, 14:R148 (18 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article RANKL synthesized by articular chondrocytes contributes to juxta-articular bone loss in chronic arthritis Maria J Martínez-Calatrava, Ivan Prieto-Potín, Jorge A Roman-Blas, Lidia Tardio, Raquel Largo, Gabriel Herrero-Beaumont Arthritis Research & Therapy 2012, 14:R149 (18 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Nafamostat mesylate, a serine protease inhibitor, demonstrates novel antimicrobial properties and effectiveness in Chlamydia-induced arthritis Robert D Inman, Basil Chiu Arthritis Research & Therapy 2012, 14:R150 (20 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Hyaluronan injection in murine osteoarthritis prevents TGFbeta 1-induced synovial neovascularization and fibrosis and maintains articular cartilage integrity by a CD44-dependent mechanism Jun Li, Daniel J Gorski, Wendy Anemaet, Jennifer Velasco, Jun Takeuchi, John D Sandy, Anna Plaas Arthritis Research & Therapy 2012, 14:R151 (21 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Aldolase predicts subsequent myopathy occurrence in systemic sclerosis Cécile Tolédano, Murielle Gain, Adrien Kettaneh, Bruno Baudin, Catherine Johanet, Patrick Chérin, Sébastien Rivière, Jean Cabane, Kiet Tiev Arthritis Research & Therapy 2012, 14:R152 (22 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Decreased hypertrophic differentiation accompanies enhanced matrix formation in co-cultures of outer meniscus cells with bone marrow mesenchymal stromal cells David JJ Saliken, Aillette Mulet-Sierra, Nadr M Jomha, Adetola B Adesida Arthritis Research & Therapy 2012, 14:R153 (22 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Analysis of the association between CD40 and CD40 ligand polymorphisms and systemic sclerosis María Teruel, Carmen P Simeon, Jasper Broen, Madelon C Vonk, Patricia Carreira, Maria Camps, Rosa García-Portales, Esmeralda Delgado-Frías, Maria Gallego, Gerard Espinosa, the Spanish Scleroderma Group, Lorenzo Beretta, Paolo Airó, Claudio Lunardi, Gabriela Riemekasten, Torsten Witte, Thomas Krieg, Alexander Kreuter, Jörg HW Distler, Nicolas Hunzelmann, Bobby P Koeleman, Alexandre E Voskuyl, Annemie J Schuerwegh, Miguel González-Gay, Timothy RDJ Radstake, Javier Martin Arthritis Research & Therapy 2012, 14:R154 (25 June 2012) Abstract \| Full text \| PDF \| PubMed
	Research article Hydroxychloroquine is associated with impaired interferon-alpha and tumor necrosis factor-alpha production by plasmacytoid dendritic cells in systemic lupus erythematosus Karim Sacre, Lindsey A Criswell, Joseph M McCune Arthritis Research & Therapy 2012, 14:R155 (27 June 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Validation of ACR/EULAR definition of remission in rheumatoid arthritis from RA practice: the ESPOIR cohort Bin Zhang, Bernard Combe, Nathalie Rincheval, David T Felson Arthritis Research & Therapy 2012, 14:R156 (29 June 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Correspondence
	Letter Response to 'Adiponectin associates with markers of cartilage degradation in osteoarthritis and induces production of proinflammatory and catabolic factors through mitogen-activated protein kinase pathways' Cengiz Korkmaz Arthritis Research & Therapy 2012, 14:402 (21 June 2012) Abstract \| Full text \| PDF \| PubMed

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