Table 1

Sample collections, proportion of women, frequencies of the three more informative AIMs and North/South score

DNA sample

Women (%)

AIM frequency (%)

N/S score


Collectiona

Control

SLE

Control

SLE

rs12913832

rs382259

rs6730157


NL

180

104

59.4

86.5

83.0

77.6

72.5

100.0

BEb

106

147

93.5

90.5

DE

95

90

n.a.

90

77.9

68.1

56.9

80.5

CZb

100

101

32

85.1

SK

93

94

93.5

91.5

72.8

63.8

39.4

64.4

HU

95

95

48.4

90.4

63.4

59.6

39.0

54.9

ES, LCG

145

88

82.9

92

35.4

67.4

45.3

47.6

ES, OVD

200

147

69

91.8

30.5

70.4

45.4

47.2

ES, SCQ

95

109

48.4

96

35.1

68.2

41.3

46.0

ES, BCN

97

90

52.6

91.1

32.6

63.2

41.6

40.5

ES, MAD

281

92

68.8

91.3

33.1

61.9

42.3

40.0

PT

97

100

91.3

95.3

28.7

60.7

39.1

34.6

IT, MXP

106

129

42.5

86.8

47.6

49.1

19.8

26.2

IT, ROM

102

84

55.9

89.7

38.2

51.9

15.3

20.3

GR, AUMS

100

95

92

91.6

36.0

44.0

13.4

11.3

IT, NAP

109

79

100

90.1

38.6

42.2

10.0

9.6

GR, EH

100

98

67

86.7

36.7

38.0

13.5

6.8


Collections are in descending order of N/S score. aCollections from: University Medical Center Groningen, The Netherlands (NL); Université Catholique de Louvain, Belgium (BE); Hannover Medical School, Germany (DE); Institute of Rheumatology, The Czech Republic (CZ); Martin Faculty Hospital, Slovakia (SK); Albert Szent-Györgyi Medical and Pharmaceutical Centre, Hungary (HU); Complexo Hospitalario Universitario A Coruña, Spain (ES, LCG); Hospital Universitario Central de Asturias, Spain (ES, OVD); Hospital Clinico Universitario de Santiago, Spain (ES, SCQ); Hospital Val d'Hebron of Barcelona, Spain (ES, BCN); Hospital 12 de Octubre, Madrid, Spain (ES, MAD); Hospital Garcia de Orta, Almada, Portugal (PT); University of Milan and Fondazione IRCCS Ospedale Maggiore Policlinico from Milan, Italy (IT, MXP), Ospedale S. Camillo - Forlanini from Roma, Italy (IT, ROM); Athens University Medical School, Athens, Greece (GR, AUMS); Second University of Naples, Italy (IT, NAP); and Evangelismos Hospital, Athens, Greece (GR, EH). bThese two collections were not analysed further because of differences in AIM frequencies between cases and controls.

Alonso-Perez et al. Arthritis Research & Therapy 2012 14:R94   doi:10.1186/ar3818

Open Data