Figure 1.

Bias for a stronger association in Southern Europeans than in Central Europeans. (A) Nine systemic lupus erythematosus (SLE) loci from Suarez-Gestal and colleagues [24]. (B) Eleven newly studied SLE-associated SNPs. Mantel-Haenszel odds ratio (OR) for the risk allele and their 95% confidence interval presented in descending order from left to right. *Loci showed significant differences between the two groups. MECP2 data only from women because it maps to the X chromosome. SNPs used for each locus are detailed in Table 2.