Table 3

Cytokine levels (pg/mL) in patients with PsA stratified by LN

n (%) of positive patients

All n = 42

LN+ n = 20 (47.6%)

LN- n = 22 (52.4%)

Wilcoxon P value


GM.CSF

4 (10%)

0 (0; 0)

0 (0; 0)

0 (0; 0)

0.051

IFN-γ

6 (14%)

0 (0; 0)

0 (0; 0)

0 (0; 0)

0.444

IL-1β

7 (7%)

0 (0; 0)

0 (0; 0)

0 (0; 0)

0.632

IL-2

21 (50%)

42 (0; 133)

0 (0; 151)

83 (0; 119)

0.851

IL-4

2 (2%)

0 (0; 0)

0 (0; 0)

0 (0; 0)

0.365

IL-5

19 (19%)

0 (0; 0)

0 (0; 0)

0 (0; 0)

0.440

IL-6

41 (98%)

1241 (503; 1,544)

1324 (764; 1,496)

1093 (258; 1,720)

0.462

IL-10

22 (52%)

4 (0; 13)

4.4 (0; 12)

0 (0; 14)

0.926

IL-12p70

0

0 (0; 0)

0 (0; 0)

0 (0; 0)

NA

IL-13

4 (10%)

0 (0; 0)

0 (0; 0)

0 (0; 0)

0.348

IL-15

38 (91%)

114 (47; 197)

180 (109; 261)

62 (23; 115)

0.002

IL-17

11 26%)

0 (0; 20)

0 (0; 7)

0 (0; 26)

0.757

IL-17F

12 (29%)

0 (0; 12)

0 (0; 6)

0 (0; 12)

0.728

IL-21

19 (45%)

0 (0; 817)

0 (0; 773)

0 (0; 958)

0.591

IL-22

1 (2%)

0 (0; 0)

0 (0; 0)

0 (0; 0)

0.317

IL-23

15 (36%)

0 (0; 212)

0 (0; 190)

0 (0; 262)

0.758

IL-28A

0

0 (0; 0)

0 (0; 0)

0 (0; 0)

NA

CCL20

34 (81%)

37 (6; 497)

23 (7; 284)

40 (1; 624)

0.752

TGF-β1

8 (19%)

0 (0; 0)

0 (0; 0)

0 (0; 446)

0.157

TNF-α

4 (10%)

0 (0; 0)

0 (0; 0)

0 (0; 0)

0.323

TNF-β

7 (17%)

0 (0; 0)

0 (0; 0)

0 (0; 0)

0.684


Data are expressed as median (IQR). NA, not applicable.

Celis et al. Arthritis Research & Therapy 2012 14:R93   doi:10.1186/ar3817

Open Data