Table 2

RT-PCR of 21 cytokine genes expressed as Delta Ct value and stratified by LN

n (%) of positive patients

All n = 46

LN+ n = 20 (43.5%)

LN- n = 26 (52.4%)

Wilcoxon P value


CCR7

45 (98%)

8 (-10; -7)

-8 (-9; -7)

-8 (-10; -7)

0.465

IFN-γ

35 (76%)

-10 (-12; -9)

-10 (-11; -9)

-11 (-12; -8)

0.656

IL-10

45 (98%)

-7 (-8; -6)

-7 (-8; -7)

-7 (-8; -6)

0.312

IL-12A

41 (89%)

-9 (-10; -8)

-9 (-10; -8)

-10 (-11; -8)

0.188

IL-13

11 (24%)

-14 (-15; -13)

-15 (-16; -15)

-13 (-14; -11)

0.109

IL-15

42 (91%)

-9 (-9; -8)

-8 (-9; -8)

-9 (-10; -8)

0.104

IL-17A

15 (33%)

-11 (-13; -9)

-13 (-14; -11)

-11 (-11; -9)

0.121

IL-18

46 (100%)

-6 (-7; -6)

-7 (-7; -6)

-6 (-7; -5)

0.418

IL-1β

43 (94%)

-8 (-9; -7)

-9 (-9; -8)

-8 (-9; -7)

0.517

IL-2

29 (59%)

-12 (-14; -11)

-13 (-14; -11)

-12 (-14; -12)

0.846

IL-21

20 (43%)

-13 (-14; -12)

-13 (-14; -12)

-13 (-14; -12)

0.909

IL-22

7 (15%)

-12 (-14; -11)

-13 (-15; -12)

-11 (-13; -11)

0.629

IL-23A

45 (98%)

-5 (-6; -5)

-5 (-6; -4)

-6 (-8; -5)

0.058

IL-28A

21 (46%)

-10 (-12; -9)

-10 (-12; -8)

-11 (-11; -10)

0.622

IL-33

41 (89%)

-11 (-12; -9)

-11 (-12; -9)

-11 (-12; -9)

0.646

IL-6

44 (96%)

-8 (-10; -6)

-8 (-9; -7)

-8 (-10; -5)

0.706

IL-7

44 (96%)

-6 (-7; -6)

-6 (-7; -5)

-7 (-7; -6)

0.608

IL-8

46 (100%)

-4 (-6; -2)

-4 (-5; -3)

-3 (-6; -2)

0.877

LTβ

44 (96%)

-6 (-8; -5)

-6 (-7; -5)

-6 (-8; -6)

0.443

TGF-β1

46 (100%)

-3 (-4; -2)

-3 (-4; -3)

-3 (-3; -2)

0.050

TNF-α

46 (100%)

-7 (-8; -6)

-7 (-8; -6)

-7 (-8; -6)

0.816


Celis et al. Arthritis Research & Therapy 2012 14:R93   doi:10.1186/ar3817

Open Data