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Table 1
Comparison of statin effects on murine collagen-induced arthritis
Study	Statin	Dose (mg/kg)	Exposure route	Timing (days)	Effect on arthritis

Present study	A	10	Oral	-28 to 20	ΔET₅₀-7 days
Present study	A	10	Oral	22 to 42	ΔET₅₀-9 days
Present study	P	40	Oral	-28 to 20	ΔET₅₀-5 days
Present study	P	40	Oral	22 to 42	ΔET₅₀-7 days
Ho and colleagues [13]	A	10	Oral	2 to 49	Suppression
Yamagata and colleagues [14]	P	100	Intraperitoneal	0 to 35	Suppression
Leung and colleagues [15]	S	40	Intraperitoneal	21 to 40	Suppression
Leung and colleagues [15]	S	20	Intraperitoneal	21 to 40	No effect
Leung and colleagues [15]	S	10	Intraperitoneal	21 to 40	No effect
Palmer and colleagues [16]	A	100	Oral	0 to 48	No effect
Palmer and colleagues [16]	A	1	Oral	0 to 48	No effect
Palmer and colleagues [16]	R	2	Subcutaneous	0 to 48	No effect
Palmer and colleagues [16]	R	0.2	Subcutaneous	0 to 48	No effect
Palmer and colleagues [16]	R	40	Intraperitoneal	21 to 35	No effect
Palmer and colleagues [16]	S	40	Intraperitoneal	21 to 35	Suppression
Palmer and colleagues [16]	S	40	Oral	21 to 35	No effect

A, atorvastatin; P, pravastatin; S, simvastatin; R, rosuvastatin; ΔET₅₀, number of days between the time when 50% of the animals developed arthritis (ET₅₀value) for the statin-treated animals and the ET₅₀value for the control animals.
Vandebriel et al. Arthritis Research & Therapy 2012 14:R90 doi:10.1186/ar3814

Table 1