Table 4 |
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Summary of the association of UBAC2 SNPs with Behcet's disease in Han Chinese population |
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First-stage |
Second-stage |
Combined study |
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|
|
|
|
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|
SNPs |
MA |
AF |
Pc Value |
OR |
95% CI |
AF |
Pc |
OR |
95% CI |
AF |
Pc |
OR |
95% CI |
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|
|
|
|
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|
Case |
Ctrl |
Case |
Ctrl |
Value |
Case |
Ctrl |
Value |
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|
|
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|
rs3825427 |
T |
116 (39.5) |
565 (29.7) |
2.2 × 10-3 |
1.5 |
1.2 to 2.0 |
248 (37.6) |
231 (30.4) |
9.3 × 10-3 |
1.4 |
1.1 to 1.7 |
364 (38.2) |
796 (29.8) |
6.9 × 10-6 |
1.5 |
1.2 to 1.7 |
|
rs9517668 |
T |
118 (41.5) |
573 (30.1) |
1.7 × 10-3 |
1.6 |
1.2 to 2.0 |
230 (34.8) |
219 (30.9) |
0.03 |
1.3 |
1.1 to 1.7 |
348 (36.5) |
792 (29.7) |
3.3 × 10-4 |
1.4 |
1.2 to 1.6 |
|
rs9517701 |
G |
117 (39.8) |
583 (30.7) |
5.1 × 10-3 |
1.5 |
1.2 to 1.9 |
249 (37.7) |
232 (30.3) |
9.0 × 10-3 |
1.4 |
1.1 to 1.7 |
366 (38.4) |
815 (30.5) |
2.9 × 10-5 |
1.4 |
1.2 to 1.7 |
|
|
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|
95% CI, confidence interval; AF, allele frequency; MA, minor allele; OR, odds ratio; Pc: Bonferroni corrected P-value. |
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|
Hou et al. Arthritis Research & Therapy 2012 14:R70 doi:10.1186/ar3789 |
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