Table 3

The meta- analysis result combined our data and Turkish data

SNP

Nearest gene

Risk allele

Population

N

Risk allele frequency

P-value

Pc value

OR (95% CI)


Cases

Controls

Cases

Controls


rs11206377

LOC100129342

G

Turkisha

152

170

66.1

51.4

3.0 × 10-4

1.5 × 10-3

1.8 (1.3 to 2.6)

(1p34)

Chinese

147

951

56.5

53.9

0.410

NS

1.1 (0.9 to 1.4)

meta-analysis

1.3 (1.1 to 1.6)

rs2061634

KIAA1529

G

Turkish

152

170

42.7

26.7

4.2 × 10-5

2.1 × 10-4

2.0 (1.5 to 2.9)

(9q22)

Chinese

147

951

79.9

80.0

0.971

NS

1.0 (0.7 to 1.4)

meta-analysis

1.4 (1.1 to 1.7)

rs317711

CPVL

C

Turkish

152

170

25.5

13.2

1.0 × 10-4

5.0 × 10-4

2.2 (1.4 to 3.3)

(7p15-p14)

Chinese

147

951

85.8

84.1

0.739

NS

1.3 (0.9 to 1.9)

meta-analysis

1.6 (1.2 to 2.1)

rs4936742

UBASH3B

T

Turkish

152

170

56.7

43.4

1.5 × 10-3

7.5 × 10-3

1.7 (1.2 to 2.4)

(11q24)

Chinese

147

951

61.5

63.2

0.590

NS

0.9 (0.7 to 1.2)

meta-analysis

1.2 (0.9 to 1.4)

rs9513584

UBAC2

G

Turkish

152

170

44.4

33.2

5.8 × 10-3

0.029

1.6 (1.2 to 2.3)

(13q32)

Chinese

147

951

51.4

42.3

3.6 × 10-3

0.018

1.4 (1.1 to 1.8)

meta-analysis

1.5(1.2 to 1.8)


aData from reference 19; OR (95% CI), Odds ratio (95%CI); NS: not significant; Pc: Bonferroni corrected P-value

Hou et al. Arthritis Research & Therapy 2012 14:R70   doi:10.1186/ar3789

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