Table 3 |
||||||||||
|
The meta- analysis result combined our data and Turkish data |
||||||||||
|
SNP |
Nearest gene |
Risk allele |
Population |
N |
Risk allele frequency |
P-value |
Pc value |
OR (95% CI) |
||
|
|
||||||||||
|
Cases |
Controls |
Cases |
Controls |
|||||||
|
|
||||||||||
|
rs11206377 |
LOC100129342 |
G |
Turkisha |
152 |
170 |
66.1 |
51.4 |
3.0 × 10-4 |
1.5 × 10-3 |
1.8 (1.3 to 2.6) |
|
(1p34) |
Chinese |
147 |
951 |
56.5 |
53.9 |
0.410 |
NS |
1.1 (0.9 to 1.4) |
||
|
meta-analysis |
1.3 (1.1 to 1.6) |
|||||||||
|
rs2061634 |
KIAA1529 |
G |
Turkish |
152 |
170 |
42.7 |
26.7 |
4.2 × 10-5 |
2.1 × 10-4 |
2.0 (1.5 to 2.9) |
|
(9q22) |
Chinese |
147 |
951 |
79.9 |
80.0 |
0.971 |
NS |
1.0 (0.7 to 1.4) |
||
|
meta-analysis |
1.4 (1.1 to 1.7) |
|||||||||
|
rs317711 |
CPVL |
C |
Turkish |
152 |
170 |
25.5 |
13.2 |
1.0 × 10-4 |
5.0 × 10-4 |
2.2 (1.4 to 3.3) |
|
(7p15-p14) |
Chinese |
147 |
951 |
85.8 |
84.1 |
0.739 |
NS |
1.3 (0.9 to 1.9) |
||
|
meta-analysis |
1.6 (1.2 to 2.1) |
|||||||||
|
rs4936742 |
UBASH3B |
T |
Turkish |
152 |
170 |
56.7 |
43.4 |
1.5 × 10-3 |
7.5 × 10-3 |
1.7 (1.2 to 2.4) |
|
(11q24) |
Chinese |
147 |
951 |
61.5 |
63.2 |
0.590 |
NS |
0.9 (0.7 to 1.2) |
||
|
meta-analysis |
1.2 (0.9 to 1.4) |
|||||||||
|
rs9513584 |
UBAC2 |
G |
Turkish |
152 |
170 |
44.4 |
33.2 |
5.8 × 10-3 |
0.029 |
1.6 (1.2 to 2.3) |
|
(13q32) |
Chinese |
147 |
951 |
51.4 |
42.3 |
3.6 × 10-3 |
0.018 |
1.4 (1.1 to 1.8) |
||
|
meta-analysis |
1.5(1.2 to 1.8) |
|||||||||
|
|
||||||||||
|
aData from reference 19; OR (95% CI), Odds ratio (95%CI); NS: not significant; Pc: Bonferroni corrected P-value |
||||||||||
|
Hou et al. Arthritis Research & Therapy 2012 14:R70 doi:10.1186/ar3789 |
||||||||||
