Figure 1.

Subject selection, illustrating the study cohort assembly. For the Kaplan-Meier analyses, we include only subjects with at least 2 years of follow-up, at least one remission time-point with subsequently 12 months or more of follow-up, and who were not in remission at entrance into BRASS. BRASS, Brigham Rheumatoid Arthritis Sequential Study; DAS28-CRP, Disease Activity Score 28-C-reactive protein; ACR, American College of Rheumatology; SDAI, Simplified Disease Activity Index; CDAI, Clinical Disease Activity; EULAR, European League Against Rheumatism.