Table 2

Proteins identified in OA synovial fluids in this study and in a previous proteomic study [10]

Protein namea

Accession no.b

Scorec

% Coveraged

Number of peptidese


Transferrin

P02787

877.49

65

57


α2-Macroglobulin

P01023

569.94

34

57


Serum albumin

P02768

514.49

60

34


Complement C3

P01024

426.92

27

34


Apolipoprotein A-I

P02647

405.32

67

26


α1-Antitrypsin (α1 protease inhibitor)

P01009

388.37

66

27


Apolipoprotein A-IV

P06727

370.16

60

27


Haptoglobin

P00738

331.09

49

22


Hemopexin (β-1B-glycoprotein)

P02790

273.36

40

20


Gc-globulin (vitamin D-binding protein precursor)

P02774

269.18

43

21


α1B-glycoprotein

P04217

215.74

47

16


Complement factor B (C3/C5 convertase)

P00751

163.54

20

12


α1-Antichymotrypsin

P01011

144.7

27

10


Antithrombin-III

P01008

142.4

32

10


Ceruloplasmin (EC 1.16.3.1) (Ferroxidase)

P00450

132.65

12

9


Transthyretin

P02766

129.52

69

8


Plasma protease C1 inhibitor

P05155

111.87

17

8


Ig mu chain C region

P01871

98.51

16

7


Actin, cytoplasmic 2 (γ-actin)

P63261

89.13

33

8


Fibrinogen β chain

P02675

88.28

18

7


α2-HS-glycoprotein

P02765

85.26

22

7


Complement factor H (H factor 1)

P08603

80.47

8

8


α1-Acid glycoprotein 1 (Orosomucoid-1)

P02763

68.98

23

5


Complement C5

P01031

55.88

8

7


Prothrombin (coagulation factor II)

P00734

52.57

9

4


Plasma retinol-binding protein

P02753

50.79

20

4


Apolipoprotein E

P02649

49.32

21

4


Afamin

P43652

48.67

7

4


Fibrinogen α chain

P02671

48.63

6

4


Gelsolin

P06396

47.03

4

3


Complement C4

P01028

39.34

8

6


Vitronectin

P04004

38.1

6

3


Apolipoprotein A-II

P02652

36.26

22

3


Hemoglobin β subunit (Hemoglobin β chain)

P68871

31.88

17

2


β2-Glycoprotein I (apolipoprotein H)

P02749

30.33

6

2


Inter-α-trypsin inhibitor heavy chain H4

Q14624

28.43

5

3


Fibronectin

P02751

23.84

2

2


Clusterin

P10909

21.17

12

2


Complement component C8 γ chain

P07360

20.93

10

2


Histidine-rich glycoprotein

P04196

20.11

5

2


Fibrinogen γ chain

P02679

19.9

7

2


Kininogen-1

P01042

16.02

4

2


Desmoplakin

P15924

11.59

1

2


α1-Microglobulin/bikunin precursor protein precursor

P02760

11.13

9

2


aShown in bold are the proteins classified as plasma proteins (as assessed by www.HPRD.org webcite). bUniProtKB/Swiss-Prot database. cAn aggregate score of the quality of the peptide spectra obtained, the total number of peptides identified, and percentage coverage of the protein. dThe number of amino acids identified as a percentage of the total number of amino acids in the corresponding protein. eThe number of peptides identified that correspond to the protein indicated.

Sohn et al. Arthritis Research & Therapy 2012 14:R7   doi:10.1186/ar3555

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