Additional file 1.

Maximum decreases in CXCL13 (pharmacodynamic effects) were consistently observed at serum pateclizumabconcentrations > 1 to 10 μg/ml across all cohorts. The pateclizumab (circles) and CXCL13 (triangles) concentrations are presented as means ± SD.

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Emu et al. Arthritis Research & Therapy 2012 14:R6   doi:10.1186/ar3554