Table 4

Organ involvement by severity of erectile dysfunction

Erectile dysfunction severity


Mild (n = 25)

Mild to moderate (n = 26)

Moderate (n = 14)

Severe (n = 40)

P value


IIEF-5 score

19 (18 to 20)

14 (13 to 16)

10 (8 to 11)

5 (5 to 6)

< 0.001*

Age (years)

50.5 (45.3 to 61.0)

54.1 (47.1 to 63.9)

54.9 (48.6 to 62.0)

57.3 (48.8 to 64.0)

< 0.001*

Duration of erectile dysfunction (years)

1.0 (0.6 to 2.3)

1.2 (0.1 to 2.6)

2.8 (0.1 to 5.0)

4.0 (1.0 to 6.4)

0.08

Diffuse SSc

59.1

47.6

72.7

82.1

0.08

C-reactive protein elevation

9.1

18.2

41.7

37.4

0.06

Forced vital capacity (% predicted)

99 (86 to 108)

100 (91 to 108)

84 (78 to 90)

81 (66 to 98)

0.006*

Forced vital capacity < 80%

16.7

6.3

33.3

47.6

0.01*

DLCO (% predicted)

70 (53 to 81)

79 (61 to 90)

64 (49 to 69)

56 (45 to 74.5)

0.02*

PAPsys (mmHg)

32 (25 to 38)

25 (21 to 29)

27 (19 to 36)

35 (25 to 39)

0.006*

PAPsys > 40 mmHg

25

10.0

16.7

38.5

0.02*

EULAR SSc activity score

1.5 (0.5 to 3.0)

2.5 (1.0 to 4.5)

3.5 (3.0 to 5.5)

2 (0.5 to 3.5)

0.047*

High SSc activity (score > 3)

26.7

47.1

83.3

40.0

0.02*


Data presented as median (interquartile range) or percentage. DLCO, diffusion capacity of the lung for carbon monoxide; IIEF-5, International Index of Erectile Function-5; PAPsys, systolic pulmonary arterial pressure; SSc, systemic sclerosis. *Significant at P < 0.05.

Foocharoen et al. Arthritis Research & Therapy 2012 14:R37   doi:10.1186/ar3748

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