Table 3

Predictors of low power Doppler activity (≤ 1) at 12 months

Univariable analyses

Multivariable analyses*


OR (95%CI)

P

OR (95% CI)

P


Overall population

CXCL13 third tertile

0.19 (0.07 to 0.54)

0.002

0.16 (0.04 to 0.58)

0.005

CRP third tertile

0.58 (0.21 to 1.56)

0.28

-

-

ESR third tertile

0.61 (0.22 to 1.7)

0.35

-

-

ACPA (positive)

0.40 (0.14 to 1.15)

0.09

0.41 (0.12 to 1.40)

0.15

baseline PD score (third tertile)

0.94 (0.31 to 2.83)

0.91

-

-

DAS < 2.4

CXCL13 third tertile

0.05 (0.01 to 0.42)

0.006

0.06 (0.01 to 0.55)

0.01

CRP third tertile

0.53 (0.12 to 2.37)

0.41

-

-

ESR third tertile

1.22 (0.22 to 6.72)

0.82

-

-

ACPA (positive)

0.46 (0.09 to 2.22)

0.33

-

-

baseline PD score (third tertile)

0.57 (0.11 to 2.86)

0.49

-

-


*Adjusted for age, gender, symptoms duration, glucocorticoid comedication, total amount of methotrexate administered and each of the variables with P < 0.2 in univariable analysis.

ACPA, anti-citrullinated protein antibodies; CRP, C-reactive protein; DAS, Disease Activity Score; ESR, erythrocyte sedimentation rate; PD, Power Doppler. CXCL13 third tertile: > 100 pg/ml. CRP third tertile: > 2.3 mg/dl. ESR third tertile: > 39 mm/1 h baseline PD score third tertile: > 7

Bugatti et al. Arthritis Research & Therapy 2012 14:R34   doi:10.1186/ar3742

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