Table 3 |
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|
Predictors of low power Doppler activity (≤ 1) at 12 months |
||||
|
Univariable analyses |
Multivariable analyses* |
|||
|
|
||||
|
OR (95%CI) |
P |
OR (95% CI) |
P |
|
|
|
||||
|
Overall population |
||||
|
CXCL13 third tertile |
0.19 (0.07 to 0.54) |
0.002 |
0.16 (0.04 to 0.58) |
0.005 |
|
CRP third tertile |
0.58 (0.21 to 1.56) |
0.28 |
- |
- |
|
ESR third tertile |
0.61 (0.22 to 1.7) |
0.35 |
- |
- |
|
ACPA (positive) |
0.40 (0.14 to 1.15) |
0.09 |
0.41 (0.12 to 1.40) |
0.15 |
|
baseline PD score (third tertile) |
0.94 (0.31 to 2.83) |
0.91 |
- |
- |
|
DAS < 2.4 |
||||
|
CXCL13 third tertile |
0.05 (0.01 to 0.42) |
0.006 |
0.06 (0.01 to 0.55) |
0.01 |
|
CRP third tertile |
0.53 (0.12 to 2.37) |
0.41 |
- |
- |
|
ESR third tertile |
1.22 (0.22 to 6.72) |
0.82 |
- |
- |
|
ACPA (positive) |
0.46 (0.09 to 2.22) |
0.33 |
- |
- |
|
baseline PD score (third tertile) |
0.57 (0.11 to 2.86) |
0.49 |
- |
- |
|
|
||||
|
*Adjusted for age, gender, symptoms duration, glucocorticoid comedication, total amount of methotrexate administered and each of the variables with P < 0.2 in univariable analysis. ACPA, anti-citrullinated protein antibodies; CRP, C-reactive protein; DAS, Disease Activity Score; ESR, erythrocyte sedimentation rate; PD, Power Doppler. CXCL13 third tertile: > 100 pg/ml. CRP third tertile: > 2.3 mg/dl. ESR third tertile: > 39 mm/1 h baseline PD score third tertile: > 7 |
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|
Bugatti et al. Arthritis Research & Therapy 2012 14:R34 doi:10.1186/ar3742 |
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