Clinical and ultrasonographic outcomes over time according to baseline CXCL13 levels. Baseline CXCL13 levels and progressive achievement of clinical and ultrasonographic (US) outcomes in patients with recent-onset rheumatoid arthritis treated within a structured treat-to-target protocol aiming at low disease activity. Patients were divided into tertiles based on CXCL13 levels. The proportion of patients achieving low disease activity (DAS < 2.4) (A) and a power Doppler score ≤ 1 at ultrasonography (B) at each time point for different CXCL13 thresholds is shown. The mean ± SD CXCL13 levels were 163.6 ± 63.27 pg/ml for the third tertile (lowest value 99.83 pg/ml), 73.57 ± 12.08 pg/ml for the second tertile and 38.44 ± 10.42 pg/ml for the first tertile. Due to the lack of significant differences between the first and the second CXCL13 tertile, clinical and US outcomes are presented together against the third tertile. Values are the mean ± SD.
Bugatti et al. Arthritis Research & Therapy 2012 14:R34 doi:10.1186/ar3742