Table 1

Descriptive statistics for all operated (ACLX) knees containing subchondral bone cysts (SBC) (Number = 8)

Time post-ACLX

CT diameter (mm)

MRI diameter (mm)

vBMD (mg/cc)

OARSI grade


Presurgical

770 ± 19

4 weeks

0.626 ± 0.126

0.656 ± 0.0781

680 ± 52

8 weeks

0.922 ± 0.111

0.827 ± 0.105

610 ± 37*

12 weeks

1.14 ± 0.0923*

1.07 ± 0.0809*

690 ± 57

18 ± 0.82

2.9 ± 0.58


Values are mean ± standard error from the measured SBC diameter and superficial volumetric bone mineral density (vBMD) occurring over time. OA grade (OARSI), acquired from the histological analysis, is provided for the final time point only and presented versus the contralateral limb score underneath. *vBMD = P < 0.05 versus presurgical, *diameter = P < 0.05 versus 4 weeks. ACLX, anterior cruciate ligament transection with partial medial meniscectomy; CT, computed tomography; MRI, magnetic resonance imaging; OARSI, Osteoarthritis Research Society International.

McErlain et al. Arthritis Research & Therapy 2012 14:R26   doi:10.1186/ar3727

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