Mean maximal diameter of subchondral bone cysts (SBC) in the medial tibial plateau for all rodents post surgery. Points represent the SBC measured in the coronal plane using micro-CT at each time point. Repeated measures ANOVA found the diameter increased significantly at 3 months post-ACLX (anterior cruciate ligament with partial medial menisectomy) versus the 1-month time point (*P < 0.05). ANOVA, analysis of variance; micro-CT, micro computed tomography.
McErlain et al. Arthritis Research & Therapy 2012 14:R26 doi:10.1186/ar3727