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Open Access Highly Accessed Research article

A randomised controlled trial of a self-management education program for osteoarthritis of the knee delivered by health care professionals

Sophie Coleman1*, N Kathryn Briffa1, Graeme Carroll234, Charles Inderjeeth45, Nicola Cook6 and Jean McQuade7

Author affiliations

1 Department of Physiotherapy, Curtin University, Beazley Avenue, Bentley, Western Australia 6102, Australia

2 Department of Rheumatology, Fremantle Hospital, Alma Street, Fremantle, Western Australia 6160, Australia

3 School of Medicine, University of Notre Dame, 13-19 Mouat Street, Fremantle, Western Australia 6160, Australia

4 School of Pharmacology and Medicine, University of Western Australia, 35 Stirling Highway, Nedlands, Western Australia 6009, Australia

5 Geriatric Medicine and Rheumatology, Sir Charles Gairdner Hospital, Verdun Street, Nedlands, Western Australia 6009, Australia

6 Rheumatology, Royal Perth Hospital, Wellington Street, Perth, Western Australia 6001, Australia

7 Arthritis Western Australia, 17 Lemnos Street, Shenton Park, Western Australia 6008, Australia

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Citation and License

Arthritis Research & Therapy 2012, 14:R21  doi:10.1186/ar3703

Published: 27 January 2012

Abstract

Introduction

Our aim in the present study was to determine whether a disease-specific self-management program for primary care patients with osteoarthritis (OA) of the knee (the Osteoarthritis of the Knee Self-Management Program (OAK)) implemented by health care professionals would achieve and maintain clinically meaningful improvements in health-related outcomes compared with a control group.

Methods

Medical practitioners referred 146 primary care patients with OA of the knee. Volunteers with coexistent inflammatory joint disease or serious comorbidities were excluded. Randomisation was to either a control group or the OAK group. The OAK group completed a 6-week self-management program. The control group had a 6-month waiting period before entering the OAK program. Assessments were taken at baseline, 8 weeks and 6 months. The primary outcomes were the results measured using the Western Ontario and McMaster Universities Arthritis Index (WOMAC) Pain and Function subscales on the Short Form 36 version 1 questionnaire (SF-36) Secondary outcomes were Visual Analogue Scale (VAS) pain, Timed Up & Go Test (TUG), knee range of motion and quadriceps and hamstring strength-isometric contraction. Responses to treatment (responders) and minimal clinically important improvements (MCIIs) were determined.

Results

In the OAK group, VAS pain improved from baseline to week 8 from mean (SEM) 5.21 (0.30) to 3.65 (0.29) (P ≤ 0.001). During this period, improvements in the OAK group compared with the control group and responses to treatment were demonstrated according to the following outcomes: WOMAC Pain, Physical Function and Total dimensions, as well as SF-36 Physical Function, Role Physical, Body Pain, Vitality and Social Functioning domains. In addition, from baseline to week 8, the proportion of MCIIs was greater among the OAK group than the control group for all outcomes. For the period between baseline and month 6, WOMAC Pain, Physical Function and Total dimensions significantly improved in the OAK group compared to the control group, as did the SF-36 Physical Function, Role Physical, Body Pain, Vitality and Social Functioning domains, as well as hamstring strength in both legs. During the same period, the TUG Test, range of motion extension and left-knee flexion improved compared with the control group, although these improvements had little clinical relevance.

Conclusions

We recorded statistically significant improvements compared with a control group with regard to pain, quality of life and function for participants in the OAK program on the basis of WOMAC and SF-36 measures taken 8 weeks and 6 months from baseline.