Table 1

Correlations between CP, PAD2, and PAD4 expression and synovial inflammation

Mean lining thickness

Infiltration

Vascularity

Total CP

0.4 (< 0.05)

0.5 (< 0.001)

0.6 (< 0.001)

Intracellular CP

0.4 (< 0.05)

0.4 (0.001)

0.6 (< 0.01)

PAD2 (ROI002)

0.5 (< 0.05)

0.6 (< 0.001)

0.4 (< 0.05)

PAD2 (SN665)

0.6 (< 0.001)

0.7 (< 0.001)

0.5 (< 0.01)

PAD4 (SG1467)

0.6 (< 0.01)

0.3 (NS)

0.3 (NS)

PAD4 (SN823)

0.5 (< 0.01)

0.1 (NS)

0.2 (NS)

Values are expressed as Spearman rank correlation coefficients (P values). CP, citrullinated protein; NS, not significant.

Makrygiannakis et al. Arthritis Research & Therapy 2012 14:R20   doi:10.1186/ar3702