Table 1

Number of pups in each group

Female swim^a

Female sedentary^b

Male swim^a

Male sedentary^b

Control^c

0.1 DES^c

1.0 DES

10.0 DES

Control

0.1 DES

1.0 DES

10.0 DES

Control

0.1 DES

1.0 DES

10.0 DES

Control

0.1 DES

1.0 DES

10.0 DES

No. of pups

8

6

8

8

9

7

5

11

6

8

5

7

11

8

7

9

^aFemale or male mice were put on a once-daily swimming regimen, which started as 5 minutes and was escalated to a maximum of 1 hour within 1 week. ^bFemale or male mice were left to their normal activity level and considered sedentary. ^cPregnant C57/bl mice were injected with either vehicle (peanut oil) or one of three doses of DES (0.1, 1.0, and 10.0 μg/kg/day) at 11 to 14 days of gestation.

Rowas et al. Arthritis Research & Therapy 2012 14:R17   doi:10.1186/ar3696