Open Access Research article

Tight regulation of wingless-type signaling in the articular cartilage - subchondral bone biomechanical unit: transcriptomics in Frzb-knockout mice

Liesbet Lodewyckx1, Frédéric Cailotto1, Sarah Thysen1, Frank P Luyten1,2 and Rik J Lories1,2*

1 Laboratory for Skeletal Development and Joint Disorders, Department of Development and Regeneration, KU Leuven, Belgium

2 Division of Rheumatology, University Hospitals Leuven, Belgium

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Arthritis Research & Therapy 2012, 14:R16 doi:10.1186/ar3695

Published: 20 January 2012

Additional files

Additional file 1:

Compiled list of WNT target genes based on the WNT Homepage.

Format: XLSX Size: 11KB Download file

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Additional file 2:

Complete list of all regulated genes and fold differences.

Format: XLSX Size: 516KB Download file

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Additional file 3:

Associations of the differentially regulated gene set using databases defining "biological processes" as analyzed by PANTHER.

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Additional file 4:

DAVID analysis of differentially expressed genes by pathway.

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Additional file 5:

GSEA analysis of all expressed genes by KEGG pathway.

Format: XLSX Size: 10KB Download file

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